SLC25A25 - solute carrier family 25 member 25 Gene

中文名称：溶质载体家族 25 成员 25

种属: Homo sapiens

同用名: MCSC; PCSCL; SCAMC2; SCAMC-2

关于 SLC25A25

功能概要

该基因编码的蛋白质属于钙结合线粒体载体家族，在 C 端具有特征性线粒体载体结构域。这些蛋白质存在于线粒体的内膜中，起着转运蛋白的作用。它们通过线粒体膜运送代谢物、核苷酸和辅助因子，从而连接和/或调节细胞质和基质功能。这种蛋白质可能作为 ATP-Mg/Pi 载体发挥作用，介导 Mg-ATP 的转运以交换磷酸盐，并且可能负责腺嘌呤核苷酸进出线粒体的净摄取或流出。已针对该基因描述了编码具有共同 C 末端但可变 N 末端的不同亚型的可变剪接转录物变体。[RefSeq 提供，2012 年 7 月]

The protein encoded by this gene belongs to the family of calcium-binding mitochondrial carriers, with a characteristic mitochondrial carrier domain at the C-terminus. These proteins are found in the inner membranes of mitochondria, and function as transport proteins. They shuttle metabolites, nucleotides and cofactors through the mitochondrial membrane and thereby connect and/or regulate cytoplasm and matrix functions. This protein may function as an ATP-Mg/Pi carrier that mediates the transport of Mg-ATP in exchange for phosphate, and likely responsible for the net uptake or efflux of adenine nucleotides into or from the mitochondria. Alternatively spliced transcript variants encoding different isoforms with a common C-terminus but variable N-termini have been described for this gene. [provided by RefSeq, Jul 2012]