1. Gene
  2. RNF157 - ring finger protein 157 Gene

RNF157 - ring finger protein 157 Gene

中文名称:无名指蛋白 157

种属: Homo sapiens

基因 ID: 114804 | 基因类型: protein coding

关于 RNF157

This gene has 10 transcripts (splice variants), 210 orthologues and 1 paralogue. Biased expression in brain (RPKM 16.0), testis (RPKM 13.4) and 11 other tissues.

功能概要

预测可启用泛素蛋白连接酶活性。预计参与多个过程,包括信号转导的负调控;树突延伸的正调控;和蛋白质自身泛素化。预测位于细胞体中。预计在早期核内体中有活性;核;和质膜。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in several processes, including negative regulation of signal transduction; positive regulation of dendrite extension; and protein autoubiquitination. Predicted to be located in cell body. Predicted to be active in early endosome; nucleus; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

RNF157 基因产物(2)

mRNA Protein Name
NM_001330501.2 NP_001317430.1 E3 ubiquitin ligase RNF157 isoform 2
NM_052916.3 NP_443148.1 E3 ubiquitin ligase RNF157 isoform 1

RNF157 蛋白结构

zf-C3HC4_3

zf-C3HC4_3: Zinc finger, C3HC4 type (RING finger) (275 - 320)

  • 0
  • 200
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  • 679 a.a.
蛋白主名 其他名称

E3 ubiquitin ligase RNF157

RING-type E3 ubiquitin transferase RNF157

关联疾病

疾病名称 别名
Testicular Leydig Cell Tumor

Testicular Leydig Cell Neoplasm

Leydig Cell Tumor Of Testis

Interstitial Cell Neoplasm Of Testis

Testicular Sex Cord-Stromal Neoplasm

Sex Cord-Stromal Tumor Of Testis

Testicular Sex Cord-Stromal Tumor

Carpenter Syndrome 1

Carpenter Syndrome

Acrocephalopolysyndactyly Type Ii

Acps Ii

CRPT1

Acrocephalopolysyndactyly Type 2

Acrocephalosyndactyly, Type Ii

Acrocephalopolysyndactyly 2

Acps2

Acps 2

Type Ii Acrocephalosyndactyly

Carpenter Syndrome, Type 1

Apert-Crouzon Disease

Patent Foramen Ovale

Atrial Septal Defect Within Oval Fossa

Foramen Ovale Patent

Ostium Secundum Atrial Septal Defect

Atrial Septal Defect, Ostium Secundum Type

Foramen Ovale, Patent

Defect, Patent Or Persistent, Ostium Secundum

Ostium Secundum Type Atrial Septal Defect

Persistent Ostium Secundum

Asd Ostium Secundum Type

Ostium Secundum Asd

Osasd

Asd, Ostium Secundum Type

Pfo - [Patent Foramen Ovale]

Open Foramen Ovale

Open Oval Foramen

Persistent Foramen Ovale

Secundum Atrial Septal Defect

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus RNF157 MGD MGI:2442484
Rattus norvegicus RNF157 RGD RGD:1591154
Felis catus RNF157 VGNC VGNC:64677
Bos taurus RNF157 VGNC VGNC:34031
Macaca mulatta RNF157 VGNC VGNC:76860
Canis familiaris RNF157 VGNC VGNC:54352