2. Gene
  3. SLC5A11 - solute carrier family 5 member 11 Gene

SLC5A11 - solute carrier family 5 member 11 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：溶质载体家族 5 成员 11

种属: Homo sapiens

同用名: KST1; RKST1; SGLT6; SMIT2

基因 ID: 115584 | 基因类型: protein coding

关于 SLC5A11

Cytogenetic location: 16p12.1 Genomic coordinates (GRCh38): 16:24,845,963-24,911,626 (from NCBI)

This gene has 11 transcripts (splice variants), 1 gene allele, 211 orthologues and 11 paralogues. Biased expression in small intestine (RPKM 3.6), brain (RPKM 1.7) and 2 other tissues.

功能概要

协同转运蛋白，如 SLC5A11，代表了一类主要的蛋白质，它们利用离子梯度驱动主动转运，以促进营养物质、神经递质、渗透质和离子的细胞积累。 (2002) [PubMed 12039040]。[OMIM 提供，2008 年 3 月]

Cotransporters, such as SLC5A11, represent a major class of proteins that make use of ion gradients to drive active transport for the cellular accumulation of nutrients, neurotransmitters, osmolytes, and ions Roll et al. (2002) [PubMed 12039040].[supplied by OMIM, Mar 2008]

SLC5A11 基因产物(21)

mRNA Protein Name
NM_001258411.3 NP_001245340.1 sodium/myo-inositol cotransporter 2 isoform 2
NM_001258412.3 NP_001245341.1 sodium/myo-inositol cotransporter 2 isoform 3
NM_001258413.3 NP_001245342.1 sodium/myo-inositol cotransporter 2 isoform 4
NM_001258414.2 NP_001245343.1 sodium/myo-inositol cotransporter 2 isoform 5
NM_001352235.2 NP_001339164.1 sodium/myo-inositol cotransporter 2 isoform 6
NM_001352236.2 NP_001339165.1 sodium/myo-inositol cotransporter 2 isoform 4
NM_001352237.2 NP_001339166.1 sodium/myo-inositol cotransporter 2 isoform 7
NM_001352238.2 NP_001339167.1 sodium/myo-inositol cotransporter 2 isoform 2
NM_001352242.2 NP_001339171.1 sodium/myo-inositol cotransporter 2 isoform 1
NM_001352245.2 NP_001339174.1 sodium/myo-inositol cotransporter 2 isoform 8
NM_001352246.2 NP_001339175.1 sodium/myo-inositol cotransporter 2 isoform 8
NM_001352247.2 NP_001339176.1 sodium/myo-inositol cotransporter 2 isoform 9
NM_001352248.3 NP_001339177.1 sodium/myo-inositol cotransporter 2 isoform 1
NM_001352249.2 NP_001339178.1 sodium/myo-inositol cotransporter 2 isoform 4
NM_001352250.2 NP_001339179.1 sodium/myo-inositol cotransporter 2 isoform 10
NM_001352259.2 NP_001339188.1 sodium/myo-inositol cotransporter 2 isoform 4
NM_001394076.1 NP_001381005.1 sodium/myo-inositol cotransporter 2 isoform 10
NM_001394077.1 NP_001381006.1 sodium/myo-inositol cotransporter 2 isoform 11
NM_001394078.1 NP_001381007.1 sodium/myo-inositol cotransporter 2 isoform 12
NM_001394079.1 NP_001381008.1 sodium/myo-inositol cotransporter 2 isoform 13
NM_001394080.1 NP_001381009.1 sodium/myo-inositol cotransporter 2 isoform 14

SLC5A11 蛋白结构

SSF

SSF: Sodium:solute symporter family (58 - 487)

  • 0
  • 200
  • 400
  • 600
  • 675 a.a.
蛋白主名 其他名称

sodium/myo-inositol cotransporter 2

Na(+)/myo-inositol cotransporter 2

关联疾病

疾病名称 别名
Systemic Lupus Erythematosus

Lupus Nephritis

SLE

Disseminated Lupus Erythematosus

Systemic Lupus Erythematosus, Susceptibility To

Lupus Erythematosus, Systemic

Lupus Nephritis, Susceptibility To

Libman-Sacks Disease

Systemic Lupus Erythematosus Susceptibility To

Sle - Lupus Erythematosus, Systemic

Le Syndrome

Lupus

Lupus Erythematosus Systemic

Lupus Erythematosus, Systemic, Susceptibility To

Lupus Vulgaris

Lupus Erythematosus, Discoid

Lupus Erythematosus

Systemic Lupus Erythematosus Nos

Sle - [Systemic Lupus Erythematosus]
Benign Familial Infantile Epilepsy

Benign Familial Infantile Seizures

Bfie

Benign Familial Infantile Convulsion

Bfic

Bfis

Benign Familial Infantile Convulsions

Familial Benign Neonatal Epilepsy

Watanabe-Vigevano Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13284 SLC5A11 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus SLC5A11 RGD RGD:621410
Macaca mulatta SLC5A11 VGNC VGNC:77759
Mus musculus SLC5A11 MGD MGI:1919316
Felis catus SLC5A11 VGNC VGNC:65400
Canis familiaris SLC5A11 VGNC VGNC:46444
Bos taurus SLC5A11 VGNC VGNC:34904
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