1. Gene
  2. CTHRC1 - collagen triple helix repeat containing 1 Gene

CTHRC1 - collagen triple helix repeat containing 1 Gene

中文名称:含胶原蛋白三股螺旋重复 1

种属: Homo sapiens

基因 ID: 115908 | 基因类型: protein coding

关于 CTHRC1

Cytogenetic location: 8q22.3 Genomic coordinates (GRCh38): 8:103,371,538-103,382,989 (from NCBI)

This gene has 4 transcripts (splice variants), 231 orthologues, 2 paralogues and is associated with 1 phenotype. Biased expression in gall bladder (RPKM 34.5), urinary bladder (RPKM 33.4) and 12 other tissues.

功能概要

该位点编码一种蛋白质,该蛋白质可能通过参与血管重塑在细胞对动脉损伤的反应中发挥作用。该位点的突变与 Barrett 食管和食管腺癌有关。已经描述了选择性剪接的转录物变体。[RefSeq 提供,2012 年 1 月]

This locus encodes a protein that may play a role in the cellular response to arterial injury through involvement in vascular remodeling. Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012]

CTHRC1 基因产物(2)

mRNA Protein Name
NM_001256099.2 NP_001243028.1 collagen triple helix repeat-containing protein 1 isoform 2
NM_138455.4 NP_612464.1 collagen triple helix repeat-containing protein 1 isoform 1 precursor

CTHRC1 蛋白结构

Collagen

Collagen: Collagen triple helix repeat (20 copies) (58 - 91)

  • 0
  • 100
  • 200
  • 243 a.a.
蛋白主名 其他名称

collagen triple helix repeat-containing protein 1

重组 CTHRC1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70092 CTHRC1 Protein, Human (HEK293, His) Q96CG8 (S31-K243) ≥95%

关联疾病

疾病名称 别名
Barrett Esophagus

Barrett'S Esophagus

Barrett Esophagus/Esophageal Adenocarcinoma

Barrett Metaplasia

Barrett'S Ulcer Of Esophagus

Ulcerative Esophagitis

Barrett'S Esophagus With Esophagitis

Barrett'S Oesophagus

Barretts Syndrome

Barrett Syndrome

BE

Peptic Ulcer Of Esophagus

Adenocarcinoma Of Esophagus

Adenocarcinoma

Adenocarcinomas

Adenoacanthoma Of Unspecified Site

Adenocarcinoid Of Unspecified Site

Adenocarcinoid Tumour Of Unspecified Site

Adenocarcinoma And Carcinoid Combined Of Unspecified Site

Adenocarcinoma Nos

Bronchiectasis 1
Gastroesophageal Reflux

Gastroesophageal Reflux Disease

Gerd

GER

Gastroesophageal Reflux, Pediatric

Acid Reflux

Gastresophageal Reflux

Gastro-Esophageal Reflux

Gerd - Gastro-Esophageal Reflux Disease

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus CTHRC1 MGD MGI:1915838
Rattus norvegicus CTHRC1 RGD RGD:628801
Macaca mulatta CTHRC1 VGNC VGNC:71436
Felis catus CTHRC1 VGNC VGNC:61251
Bos taurus CTHRC1 VGNC VGNC:27796
Canis familiaris CTHRC1 VGNC VGNC:49728
Others CTHRC1 NCBI