F2rl1 - F2R like trypsin receptor 1 Gene

中文名称：F2 R 样胰蛋白酶受体 1

种属: Rattus norvegicus

同用名: Par2; Par-2

关于 F2rl1

功能概要

预计该基因编码的蛋白可启动 G 蛋白偶联受体活性； G蛋白α-亚基结合活性；和 G 蛋白 β-亚基结合活性。参与肾小球滤过的正调节。在血管舒张的上游或内部发挥积极作用。预计位于早期核内体；质膜;和伪讲台。预计是质膜的组成部分。肺病的生物标志物。与哮喘有关的该基因的人类直系同源物；慢性阻塞性肺疾病;和呼吸道过敏。与人 F2RL1（F2R 样胰蛋白酶受体 1）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable G protein-coupled receptor activity; G-protein alpha-subunit binding activity; and G-protein beta-subunit binding activity. Involved in positive regulation of glomerular filtration. Acts upstream of or within with a positive effect on vasodilation. Predicted to be located in early endosome; plasma membrane; and pseudopodium. Predicted to be integral component of plasma membrane. Biomarker of lung disease. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; and respiratory allergy. Orthologous to human F2RL1 (F2R like trypsin receptor 1). [provided by Alliance of Genome Resources, Apr 2022]