2. Gene
  3. FAT3 - FAT atypical cadherin 3 Gene

FAT3 - FAT atypical cadherin 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：FAT 非典型钙粘蛋白 3

种属: Homo sapiens

同用名: hFat3; CDHF15; CDHR10

基因 ID: 120114 | 基因类型: protein coding

关于 FAT3

Cytogenetic location: 11q14.3 Genomic coordinates (GRCh38): 11:92,224,818-92,896,473 (from NCBI)

This gene has 6 transcripts (splice variants), 317 orthologues, 6 paralogues and is associated with 124 phenotypes. Biased expression in brain (RPKM 1.5), prostate (RPKM 0.4) and 7 other tissues.

功能概要

预测可启用钙离子结合活性。预计参与细胞间粘附。预计在几个过程的上游或内部起作用，包括对枝晶发育的负调节；神经元迁移；和视网膜层形成。预测位于树突和质膜中。预计是膜的组成部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to act upstream of or within several processes, including negative regulation of dendrite development; neuron migration; and retina layer formation. Predicted to be located in dendrite and plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

FAT3 基因产物(3)

mRNA Protein Name
NM_001008781.3 NP_001008781.2 protocadherin Fat 3 isoform 2 precursor
NM_001367949.2 NP_001354878.1 protocadherin Fat 3 isoform 1 precursor
NM_001378141.1 NP_001365070.1 protocadherin Fat 3 isoform 3 precursor

FAT3 蛋白结构

Cadherin

Cadherin: Cadherin domain (163 - 256)

Cadherin

Cadherin: Cadherin domain (477 - 568)

Cadherin

Cadherin: Cadherin domain (733 - 822)

Cadherin

Cadherin: Cadherin domain (836 - 924)

Cadherin

Cadherin: Cadherin domain (941 - 1031)

Cadherin

Cadherin: Cadherin domain (1050 - 1139)

Cadherin

Cadherin: Cadherin domain (1157 - 1245)

Cadherin

Cadherin: Cadherin domain (1259 - 1348)

Cadherin

Cadherin: Cadherin domain (1465 - 1557)

Cadherin

Cadherin: Cadherin domain (1571 - 1662)

Cadherin

Cadherin: Cadherin domain (1676 - 1759)

Cadherin

Cadherin: Cadherin domain (1792 - 1872)

Cadherin

Cadherin: Cadherin domain (1987 - 2075)

Cadherin

Cadherin: Cadherin domain (2096 - 2178)

Cadherin

Cadherin: Cadherin domain (2191 - 2273)

Cadherin

Cadherin: Cadherin domain (2292 - 2384)

Cadherin

Cadherin: Cadherin domain (2401 - 2487)

Cadherin

Cadherin: Cadherin domain (2501 - 2590)

Cadherin

Cadherin: Cadherin domain (2605 - 2699)

Cadherin

Cadherin: Cadherin domain (2822 - 2915)

Cadherin

Cadherin: Cadherin domain (2929 - 3007)

Cadherin

Cadherin: Cadherin domain (3034 - 3110)

Cadherin

Cadherin: Cadherin domain (3137 - 3227)

Cadherin

Cadherin: Cadherin domain (3241 - 3331)

Cadherin

Cadherin: Cadherin domain (3346 - 3436)

Cadherin

Cadherin: Cadherin domain (3451 - 3541)

Laminin_G_2

Laminin_G_2: Laminin G domain (3865 - 3993)

EGF_CA

EGF_CA: Calcium-binding EGF domain (4098 - 4129)

  • 0
  • 800
  • 1600
  • 2400
  • 3200
  • 4000
  • 4589 a.a.
蛋白主名 其他名称

protocadherin Fat 3

FAT tumor suppressor homolog 3

关联疾病

疾病名称 别名
Spinocerebellar Ataxia 45

SCA45

Spinocerebellar Ataxia Type 45
Classic Pulmonary Blastoma

Biphasic Pulmonary Blastoma
Van Maldergem Syndrome

Van Maldergem Wetzburger Verloes Syndrome

Cerebro-Facio-Articular Syndrome

Cerebro-Facio-Articular Syndrome Of Van Maldergem

Cerebrofacioarticular Syndrome

Cerebro Facio Articular Syndrome

Van Maldergem-Wetzburger-Verloes Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04762 FAT3 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-W009544 3-Hydroxytetradecanoic acid / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus FAT3 MGD MGI:2444314
Canis familiaris FAT3 VGNC VGNC:40744
Felis catus FAT3 VGNC VGNC:62159
Bos taurus FAT3 VGNC VGNC:28876
Rattus norvegicus FAT3 RGD RGD:620657
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z