2. Gene
  3. APOBEC3D - apolipoprotein B mRNA editing enzyme catalytic subunit 3D Gene

APOBEC3D - apolipoprotein B mRNA editing enzyme catalytic subunit 3D Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：载脂蛋白 B mRNA 编辑酶催化亚基 3D

种属: Homo sapiens

同用名: A3D; A3DE; ARP6; APOBEC3E; APOBEC3DE

基因 ID: 140564 | 基因类型: protein coding

关于 APOBEC3D

Cytogenetic location: 22q13.1 Genomic coordinates (GRCh38): 22:39,021,127-39,033,277 (from NCBI)

This gene has 3 transcripts (splice variants), 48 orthologues and 9 paralogues. Broad expression in lymph node (RPKM 5.2), spleen (RPKM 4.6) and 22 other tissues.

功能概要

该基因是胞苷脱氨酶基因家族的成员。它是在一个簇中发现的一组相关基因之一，被认为是由 22 号染色体上的基因复制引起的。该簇的成员编码的蛋白质在结构和功能上与 C 到 U RNA 编辑胞苷脱氨酶 APOBEC1 相关，并抑制通过使新生逆转录病毒 cDNA 中的胞嘧啶残基脱氨基来去除逆转录病毒，例如 HIV。[RefSeq 提供，2008 年 7 月]

This gene is a member of the cytidine deaminase gene family. It is one of a group of related genes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1 and inhibit retroviruses, such as HIV, by deaminating cytosine residues in nascent retroviral cDNA. [provided by RefSeq, Jul 2008]

APOBEC3D 基因产物(2)

mRNA Protein Name
NM_001363781.1 NP_001350710.1 DNA dC->dU-editing enzyme APOBEC-3D isoform 2
NM_152426.4 NP_689639.2 DNA dC->dU-editing enzyme APOBEC-3D isoform 1

APOBEC3D 蛋白结构

APOBEC_N

APOBEC_N: APOBEC-like N-terminal domain (68 - 197)

APOBEC_N

APOBEC_N: APOBEC-like N-terminal domain (216 - 384)

  • 0
  • 100
  • 200
  • 300
  • 386 a.a.
蛋白主名 其他名称

DNA dC->dU-editing enzyme APOBEC-3D

apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D

关联疾病

疾病名称 别名
Brachydactyly, Type A3

Brachydactyly Type A3

BDA3

Brachydactyly-Clinodactyly

Brachymesophalangy V

Brachymesophalangy 5

Brachydactyly Clinodactyly
Bone Giant Cell Sarcoma

Giant Cell Sarcoma Of The Bone

Giant Cell Tumor Of Bone, Malignant
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00838 APOBEC3D Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus APOBEC3D MGD MGI:1933111
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