1. Gene
  2. NEURL2 - neuralized E3 ubiquitin protein ligase 2 Gene

NEURL2 - neuralized E3 ubiquitin protein ligase 2 Gene

中文名称:神经化 E3 泛素蛋白连接酶 2

种属: Homo sapiens

同用名: OZZ; OZZ-E3; C20orf163

基因 ID: 140825 | 基因类型: protein coding

关于 NEURL2

Cytogenetic location: 20q13.12 Genomic coordinates (GRCh38): 20:45,888,634-45,891,208 (from NCBI)

This gene has 2 transcripts (splice variants) and 185 orthologues. Ubiquitous expression in kidney (RPKM 2.2), ovary (RPKM 2.0) and 25 other tissues.

功能概要

该基因编码一种参与肌原纤维组织调节的蛋白质。这种蛋白质可能是横纹肌中 E3 泛素连接酶复合物的衔接子成分,它在肌生成过程中调节泛素介导的 β-连环蛋白降解。该基因的可变剪接导致多个转录变体。[RefSeq 提供,2013 年 6 月]

This gene encodes a protein that is involved in the regulation of myofibril organization. This protein is likely the adaptor component of the E3 ubiquitin ligase complex in striated muscle, and it regulates the ubiquitin-mediated degradation of beta-catenin during myogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jun 2013]

NEURL2 基因产物(2)

mRNA Protein Name
NM_001278535.2 NP_001265464.1 neuralized-like protein 2 isoform 2
NM_080749.4 NP_542787.1 neuralized-like protein 2 isoform 1

NEURL2 蛋白结构

Neuralized

Neuralized: Neuralized (24 - 90)

SOCS_box

SOCS_box: SOCS box (249 - 285)

  • 0
  • 100
  • 200
  • 285 a.a.
蛋白主名 其他名称

neuralized-like protein 2

neuralized homolog 2

直系同源

种属 基因名 来源 基因 ID
Felis catus NEURL2 VGNC VGNC:81131
Bos taurus NEURL2 VGNC VGNC:32015
Canis familiaris NEURL2 VGNC VGNC:43751
Rattus norvegicus NEURL2 RGD RGD:1306409
Mus musculus NEURL2 MGD MGI:3043305
Macaca mulatta NEURL2 VGNC VGNC:107824