1. Gene
  2. STK35 - serine/threonine kinase 35 Gene

STK35 - serine/threonine kinase 35 Gene

中文名称:丝氨酸/苏氨酸激酶 35

种属: Homo sapiens

同用名: CLIK1; STK35L1

基因 ID: 140901 | 基因类型: protein coding

关于 STK35

Cytogenetic location: 20p13 Genomic coordinates (GRCh38): 20:2,101,827-2,148,555 (from NCBI)

This gene has 2 transcripts (splice variants), 261 orthologues and 8 paralogues. Ubiquitous expression in testis (RPKM 8.0), esophagus (RPKM 4.7) and 25 other tissues.

功能概要

该基因编码的蛋白质是一种主要存在于细胞核中的激酶。然而,它可以与细胞质中的 PDLIM1/CLP-36 相互作用并定位于肌动蛋白应力纤维。编码的蛋白质可能是非肌肉细胞中肌动蛋白应力纤维的调节剂。[RefSeq 提供,2008 年 7 月]

The protein encoded by this gene is a kinase that is predominantly found in the nucleus. However, it can interact with PDLIM1/CLP-36 in the cytoplasm and localize to actin stress fibers. The encoded protein may be a regulator of actin stress fibers in nonmuscle cells. [provided by RefSeq, Jul 2008]

STK35 基因产物(1)

mRNA Protein Name
NM_080836.4 NP_543026.2 serine/threonine-protein kinase 35

STK35 蛋白结构

Pkinase

Pkinase: Protein kinase domain (202 - 523)

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  • 534 a.a.
蛋白主名 其他名称

serine/threonine-protein kinase 35

CLIK-1

直系同源

种属 基因名 来源 基因 ID
Felis catus STK35 VGNC VGNC:65784
Macaca mulatta STK35 VGNC VGNC:78134
Bos taurus STK35 VGNC VGNC:35397
Rattus norvegicus STK35 RGD RGD:1310247
Canis familiaris STK35 VGNC VGNC:46917
Mus musculus STK35 MGD MGI:1914583