CSTF3 - cleavage stimulation factor subunit 3 Gene

中文名称：裂解刺激因子亚基 3

种属: Homo sapiens

同用名: CSTF-77

关于 CSTF3

功能概要

由该基因编码的蛋白质是三种 (包括 CSTF1 和 CSTF2) 切割刺激因子之一，它们结合形成切割刺激因子复合物 (CSTF) 。该复合物参与前体 mRNA 的聚腺苷酸化和 3' 末端切割。编码的蛋白质作为同型二聚体发挥作用，并与 CSTF 复合体中的 CSTF1 和 CSTF2 直接相互作用。可变剪接导致编码不同异构体的多个转录变体。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is one of three (including CSTF1 and CSTF2) cleavage stimulation factors that combine to form the cleavage stimulation factor complex (CSTF). This complex is involved in the polyadenylation and 3' end cleavage of pre-mRNAs. The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]