2. Gene
  3. TCF23 - transcription factor 23 Gene

TCF23 - transcription factor 23 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：转录因子 23

种属: Homo sapiens

同用名: OUT; TCF-23; bHLHa24

基因 ID: 150921 | 基因类型: protein coding

关于 TCF23

Cytogenetic location: 2p23.3 Genomic coordinates (GRCh38): 2:27,149,004-27,156,974 (from NCBI)

This gene has 2 transcripts (splice variants), 180 orthologues and 13 paralogues. Biased expression in endometrium (RPKM 12.5), ovary (RPKM 9.5) and 2 other tissues.

功能概要

该基因编码基本螺旋-环-螺旋转录因子家族的成员。对小鼠直向同源基因的研究表明，编码的蛋白质不结合 DNA，但可能通过形成功能失活的异二聚体复合物来负向调节其他基本螺旋-环-螺旋因子。[RefSeq 提供，2010 年 5 月]

The gene encodes a member of the basic helix-loop-helix transcription factor family. Studies of the orthologous gene in mouse have shown the encoded protein does not bind DNA but may negatively regulate other basic helix-loop-helix factors via the formation of a functionally inactive heterodimeric complex. [provided by RefSeq, May 2010]

TCF23 基因产物(1)

mRNA Protein Name
NM_175769.3 NP_786951.1 transcription factor 23

TCF23 蛋白结构

HLH

HLH: Helix-loop-helix DNA-binding domain (82 - 128)

  • 0
  • 100
  • 200
  • 214 a.a.
蛋白主名 其他名称

transcription factor 23

class A basic helix-loop-helix protein 24

关联疾病

疾病名称 别名
Retinal Arteries, Tortuosity Of

Retinal Arterial Tortuosity

Retinal Hemorrhage With Vascular Tortuosity

RATOR

Tortuosity Of Retinal Arteries

Retinal Arteriolar Tortuosity

Familial Isolated Retinal Arterial Tortuosity

Tortuosity, Arteries, Retinal
Ras-Associated Autoimmune Leukoproliferative Disorder

RALD

Autoimmune Lymphoproliferative Syndrome Type 4

Alps4

Autoimmune Lymphoproliferative Syndrome, Type Iv

Ras-Associated Autoimmune Leukoproliferative Disease

Ras-Associated Autoimmune Lymphoproliferative Syndrome Type Iv, Somatic

Alps Type 4

Alps Type Iv

Autoimmune Lymphoproliferative Syndrome Type Iv

Autoimmune Lymphoproliferative Syndrome 4
Fanconi Anemia, Complementation Group E

Fanconi Anemia Complementation Group E

FANCE

Face

Faces Syndrome
Western Equine Encephalitis

Western Equine Encephalomyelitis

Wee

Encephalomyelitis, Western Equine

Western Equine Encephalitis Virus Infection

Wee - [Western Equine Encephalitis]

Western Equine Encephalitis Virus
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14304 TCF23 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus TCF23 VGNC VGNC:35691
Felis catus TCF23 VGNC VGNC:81235
Macaca mulatta TCF23 VGNC VGNC:79156
Rattus norvegicus TCF23 RGD RGD:1586500
Canis familiaris TCF23 VGNC VGNC:47194
Mus musculus TCF23 MGD MGI:1934960
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