2. Gene
  3. FGD5 - FYVE, RhoGEF and PH domain containing 5 Gene

FGD5 - FYVE, RhoGEF and PH domain containing 5 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 FYVE、RhoGEF 和 PH 域 5

种属: Homo sapiens

同用名: ZFYVE23

基因 ID: 152273 | 基因类型: protein coding

关于 FGD5

Cytogenetic location: 3p25.1 Genomic coordinates (GRCh38): 3:14,810,688-14,934,571 (from NCBI)

This gene has 7 transcripts (splice variants), 270 orthologues and 10 paralogues. Broad expression in spleen (RPKM 15.9), lung (RPKM 13.8) and 22 other tissues.

功能概要

预测可实现胍基核苷酸交换因子活性和小 GTP 酶结合活性。预计将参与多个过程，包括丝状足的组装；调节 GTPase 活性；和细胞形状的调节。位于质膜。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in several processes, including filopodium assembly; regulation of GTPase activity; and regulation of cell shape. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

FGD5 基因产物(2)

mRNA Protein Name
NM_001320276.2 NP_001307205.1 FYVE, RhoGEF and PH domain-containing protein 5 isoform 2
NM_152536.4 NP_689749.3 FYVE, RhoGEF and PH domain-containing protein 5 isoform 1

FGD5 蛋白结构

RhoGEF

RhoGEF: RhoGEF domain (896 - 1083)

PH

PH: PH domain (1116 - 1205)

FYVE

FYVE: FYVE zinc finger (1240 - 1301)

PH

PH: PH domain (1366 - 1459)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1462 a.a.
蛋白主名 其他名称

FYVE, RhoGEF and PH domain-containing protein 5

zinc finger FYVE domain-containing protein 23

关联疾病

疾病名称 别名
Aarskog-Scott Syndrome

Aarskog Syndrome

Faciogenital Dysplasia

Faciodigitogenital Syndrome

AAS

Fgdy

X-Linked Aarskog Syndrome

Intellectual Developmental Disorder, X-Linked, Syndromic 16

Aarskog Syndrome, X-Linked

Intellectual Developmental Disorder, X-Linked Syndromic 16

Greig'S Syndrome

Aarskog Scott Syndrome

Aarskog Disease

Scott Aarskog Syndrome

Facio-Digito-Genital Dysplasia

Faciogenital Dysplasia With Attention Deficit-Hyperactivity Disorder

Aarskog-Scott Syndrome ) Syndrome
Gastroduodenitis
Breast Abscess

Abscess Of Breast
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04884 FGD5 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus FGD5 MGD MGI:2443369
Canis familiaris FGD5 VGNC VGNC:40837
Rattus norvegicus FGD5 RGD RGD:1305589
Macaca mulatta FGD5 VGNC VGNC:72533
Bos taurus FGD5 VGNC VGNC:28968
Felis catus FGD5 VGNC VGNC:62243
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