1. Gene
  2. SLC2A12 - solute carrier family 2 member 12 Gene

SLC2A12 - solute carrier family 2 member 12 Gene

中文名称:溶质载体家族 2 成员 12

种属: Homo sapiens

同用名: GLUT8; GLUT12

基因 ID: 154091 | 基因类型: protein coding

关于 SLC2A12

Cytogenetic location: 6q23.2 Genomic coordinates (GRCh38): 6:133,987,581-134,052,624 (from NCBI)

This gene has 1 transcript (splice variant), 289 orthologues and 13 paralogues. Broad expression in prostate (RPKM 9.5), endometrium (RPKM 4.6) and 18 other tissues.

功能概要

SLC2A12 属于通过促进扩散催化糖摄取的转运蛋白家族 (Rogers 等人,2002) 。该转运蛋白家族显示出 12 个跨膜螺旋以及功能上重要的氨基酸残基的保守性 (Joost 和 Thorens,2001 [PubMed 11780753]) 。[OMIM 提供,2008 年 3 月]

SLC2A12 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion (Rogers et al., 2002). This family of transporters show conservation of 12 transmembrane helices as well as functionally significant amino acid residues (Joost and Thorens, 2001 [PubMed 11780753]).[supplied by OMIM, Mar 2008]

SLC2A12 基因产物(1)

mRNA Protein Name
NM_145176.3 NP_660159.1 solute carrier family 2, facilitated glucose transporter member 12

SLC2A12 蛋白结构

Sugar_tr

Sugar_tr: Sugar (and other) transporter (45 - 365)

Sugar_tr

Sugar_tr: Sugar (and other) transporter (462 - 562)

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  • 617 a.a.
蛋白主名 其他名称

solute carrier family 2, facilitated glucose transporter member 12

GLUT-12

关联疾病

疾病名称 别名
Arterial Tortuosity Syndrome

Arterial Tortuosity

Ats

ATORS

Tortuosity, Arterial, Syndrome

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus SLC2A12 VGNC VGNC:34798
Mus musculus SLC2A12 MGD MGI:3052471
Rattus norvegicus SLC2A12 RGD RGD:1310175
Felis catus SLC2A12 VGNC VGNC:65301
Macaca mulatta SLC2A12 VGNC VGNC:77503
Canis familiaris SLC2A12 VGNC VGNC:46339