1. Gene
  2. Hsph1 - heat shock 105kDa/110kDa protein 1 Gene

Hsph1 - heat shock 105kDa/110kDa protein 1 Gene

中文名称:热休克 105 kDa/110 kDa 蛋白 1

种属: Mus musculus

同用名: 105kDa; Hsp105; Hsp110; hsp-E7I; hsp110/105

基因 ID: 15505 | 基因类型: protein coding

关于 Hsph1

Chromosome 5: 149,537,752-149,559,841 reverse strand.GRCm39:CM000998.3

This gene has 11 transcripts (splice variants), 158 orthologues, 12 paralogues and is associated with 3 phenotypes. Broad expression in cortex adult (RPKM 3.2), CNS E11.5 (RPKM 29.9) and 25 other tissues.


该基因编码的蛋白可启动 α-微管蛋白结合活性。作用于多个过程的上游或内部,包括伴侣辅因子依赖性蛋白质重折叠;细胞内信号转导的负调节;氮化合物代谢过程的正向调控。位于细胞质和细胞核中。与微管共定位。以多种结构表达,包括大脑;直觉;外皮系统;肝脏和胆道系统;和生殖系统。与人类 HSPH1(热休克蛋白家族 H (Hsp110) 成员 1)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables alpha-tubulin binding activity. Acts upstream of or within several processes, including chaperone cofactor-dependent protein refolding; negative regulation of intracellular signal transduction; and positive regulation of nitrogen compound metabolic process. Located in cytoplasm and nucleus. Colocalizes with microtubule. Is expressed in several structures, including brain; gut; integumental system; liver and biliary system; and reproductive system. Orthologous to human HSPH1 (heat shock protein family H (Hsp110) member 1). [provided by Alliance of Genome Resources, Apr 2022]

Hsph1 基因产物(2)

mRNA Protein Name
NM_013559.2 NP_038587.2 heat shock protein 105 kDa isoform 1
NM_001347534.1 NP_001334463.1 heat shock protein 105 kDa isoform 2

Hsph1 蛋白结构


HSPH1_NBD: cd11739 (1 - 383)


FtsN: cl34549 (517 - 600)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 858 a.a.
蛋白主名 其他名称

heat shock protein 105 kDa

42 degrees C-HSP

HSP105 42 C-HSP

heat shock 110 kDa protein

heat shock protein 110

heat shock-related 100 kDa protein E7I


种属 基因名 来源 基因 ID
Homo sapiens Hsph1 NCBI NCBI:10808