CHST13 - carbohydrate sulfotransferase 13 Gene

中文名称：碳水化合物磺基转移酶 13

种属: Homo sapiens

同用名: C4ST3

关于 CHST13

功能概要

该基因编码的蛋白质属于磺基转移酶 2 家族。它定位于高尔基体膜，催化硫酸盐转移到 β-1,4-连接的 N-乙酰半乳糖胺 (GalNAc) 的 C4 羟基，两侧是软骨素中的葡萄糖醛酸残基。硫酸软骨素构成软骨中存在的主要蛋白多糖，分布在许多细胞和细胞外基质的表面。[RefSeq 提供，2011 年 8 月]

The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to the C4 hydroxyl of beta-1,4-linked N-acetylgalactosamine (GalNAc) flanked by glucuronic acid residue in chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. [provided by RefSeq, Aug 2011]