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  2. Mapk11 - mitogen-activated protein kinase 11 Gene

Mapk11 - mitogen-activated protein kinase 11 Gene

中文名称:丝裂原活化蛋白激酶 11

种属: Mus musculus

同用名: P38b; Sapk2; p38-2; Prkm11; Sapk2b; p38beta; p38beta2

基因 ID: 19094 | 基因类型: protein coding

关于 Mapk11

Chromosome 15: 89,026,689-89,033,831 reverse strand.GRCm39:CM001008.3

This gene has 4 transcripts (splice variants), 201 orthologues, 19 paralogues and is associated with 3 phenotypes. Broad expression in cortex adult (RPKM 22.5), CNS E14 (RPKM 2.2) and 2 other tissues.

功能概要

该基因编码的蛋白可启动 MAP 激酶活性。参与MAPK级联;骨骼发育;和成骨细胞分化。在心肌细胞增殖的负调节上游或负调节中起作用。在胞质溶胶中有活性。在泌尿生殖系统中表达;肺;神经系统;和感觉器官。与人 MAPK11(丝裂原活化蛋白激酶 11)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables MAP kinase activity. Involved in MAPK cascade; bone development; and osteoblast differentiation. Acts upstream of or within negative regulation of cardiac muscle cell proliferation. Is active in cytosol. Is expressed in genitourinary system; lung; nervous system; and sensory organ. Orthologous to human MAPK11 (mitogen-activated protein kinase 11). [provided by Alliance of Genome Resources, Apr 2022]

Mapk11 基因产物(1)

mRNA Protein Name
NM_011161.5 NP_035291.4 mitogen-activated protein kinase 11
蛋白主名 其他名称

mitogen-activated protein kinase 11

MAP kinase 11

MAP kinase p38 beta

MAPK 11

mitogen-activated protein kinase p38 beta

protein kinase, mitogen activated kinase, 11, p38beta

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mapk11 NCBI NCBI:5600