2. Gene
  3. PATL2 - PAT1 homolog 2 Gene

PATL2 - PAT1 homolog 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：PAT1 同系物 2

种属: Homo sapiens

同用名: OOMD4; Pat1a; hPat1a

基因 ID: 197135 | 基因类型: protein coding

关于 PATL2

Cytogenetic location: 15q21.1 Genomic coordinates (GRCh38): 15:44,665,732-44,711,390 (from NCBI)

This gene has 9 transcripts (splice variants), 1 gene allele, 179 orthologues, 1 paralogue and is associated with 2 phenotypes. Broad expression in spleen (RPKM 2.6), lymph node (RPKM 2.5) and 20 other tissues.

功能概要

预测启用 RNA 结合活性。预测参与 P 体组装和核转录 mRNA 的脱腺苷酸化依赖性脱帽。预计在细胞质 mRNA 加工体组装的负调节上游或负调节内起作用。位于细胞质中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable RNA binding activity. Predicted to be involved in P-body assembly and deadenylation-dependent decapping of nuclear-transcribed mRNA. Predicted to act upstream of or within negative regulation of cytoplasmic mRNA processing body assembly. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

PATL2 基因产物(7)

mRNA Protein Name
NM_001145112.2 NP_001138584.1 protein PAT1 homolog 2 isoform 1
NM_001330283.2 NP_001317212.1 protein PAT1 homolog 2 isoform 2
NM_001387260.1 NP_001374189.1 protein PAT1 homolog 2 isoform 3
NM_001387261.1 NP_001374190.1 protein PAT1 homolog 2 isoform 1
NM_001387262.1 NP_001374191.1 protein PAT1 homolog 2 isoform 1
NM_001387263.1 NP_001374192.1 protein PAT1 homolog 2 isoform 1
NM_001387264.1 NP_001374193.1 protein PAT1 homolog 2 isoform 3

PATL2 蛋白结构

PAT1

PAT1: Topoisomerase II-associated protein PAT1 (150 - 227)

PAT1

PAT1: Topoisomerase II-associated protein PAT1 (254 - 490)

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  • 500
  • 543 a.a.
蛋白主名 其他名称

protein PAT1 homolog 2

PAT1-like protein 2

关联疾病

疾病名称 别名
Oocyte Maturation Defect 4

OOMD4

Oocyte Maturation Defect, Type 4
Female Infertility Due To Oocyte Meiotic Arrest
Oocyte Maturation Defect 2

OOMD2

Oocyte Maturation Defect, Type 2
Infertility
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10085 PATL2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus PATL2 RGD RGD:1307887
Canis familiaris PATL2 VGNC VGNC:44273
Bos taurus PATL2 VGNC VGNC:32594
Mus musculus PATL2 MGD MGI:1914828
Macaca mulatta PATL2 VGNC VGNC:75708
Felis catus PATL2 VGNC VGNC:64050
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