2. Gene
  3. ELF2 - E74 like ETS transcription factor 2 Gene

ELF2 - E74 like ETS transcription factor 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：E74 样 ETS 转录因子 2

种属: Homo sapiens

同用名: EU32; NERF; NERF-2; NERF-1A; NERF-1B; NERF-1a,b

基因 ID: 1998 | 基因类型: protein coding

关于 ELF2

Cytogenetic location: 4q31.1 Genomic coordinates (GRCh38): 4:139,057,220-139,177,915 (from NCBI)

This gene has 13 transcripts (splice variants), 200 orthologues and 28 paralogues. Ubiquitous expression in testis (RPKM 17.8), bone marrow (RPKM 13.2) and 25 other tissues.

功能概要

启用 DNA 结合转录因子活性、RNA 聚合酶 II 特异性和序列特异性双链 DNA 结合活性。参与转录的负调控，以 DNA 为模板；转录的正调控，DNA 模板化； RNA 聚合酶 II 对转录的调控。位于细胞质和核体中。 [由基因组资源联盟提供，2022 年 4 月]

Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of transcription, DNA-templated; positive regulation of transcription, DNA-templated; and regulation of transcription by RNA polymerase II. Located in cytosol and nuclear body. [provided by Alliance of Genome Resources, Apr 2022]

ELF2 基因产物(11)

mRNA Protein Name
NM_001276457.2 NP_001263386.1 ETS-related transcription factor Elf-2 isoform 3
NM_001276458.3 NP_001263387.1 ETS-related transcription factor Elf-2 isoform 4
NM_001276459.3 NP_001263388.1 ETS-related transcription factor Elf-2 isoform 5
NM_001331036.3 NP_001317965.1 ETS-related transcription factor Elf-2 isoform 6
NM_001371324.1 NP_001358253.1 ETS-related transcription factor Elf-2 isoform 1
NM_001371336.1 NP_001358265.1 ETS-related transcription factor Elf-2 isoform 7
NM_001371337.1 NP_001358266.1 ETS-related transcription factor Elf-2 isoform 8
NM_001371338.1 NP_001358267.1 ETS-related transcription factor Elf-2 isoform 9
NM_001371339.1 NP_001358268.1 ETS-related transcription factor Elf-2 isoform 10
NM_006874.5 NP_006865.1 ETS-related transcription factor Elf-2 isoform 2
NM_201999.3 NP_973728.1 ETS-related transcription factor Elf-2 isoform 1

ELF2 蛋白结构

Elf-1_N

Elf-1_N: Transcription factor protein N terminal (3 - 108)

Ets

Ets: Ets-domain (208 - 290)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 593 a.a.
蛋白主名 其他名称

ETS-related transcription factor Elf-2

E74-like factor 2 (ets domain transcription factor)

关联疾病

疾病名称 别名
Cerebellar Ataxia, Neuropathy, And Vestibular Areflexia Syndrome

CANVAS

Cerebellar Ataxia With Neuropathy And Bilateral Vestibular Areflexia Syndrome

Cabv Syndrome

Cerebellar Ataxia With Bilateral Vestibulopathy Syndrome

Ataxia, Cerebellar, Neuropathy, And Vestibular Areflexia Syndrome
Adie Pupil

Adie Syndrome

Holmes-Adie Syndrome

Poorly Reacting Pupils

Adie'S Pupil Or Syndrome

Adie'S Pupil Syndrome

Adie'S Syndrome

Adie'S Pupil

Has

Tonic, Sluggishly Reacting Pupil And Hypoactive Or Absent Tendon Reflexes

Tonic Pupil-Tendon Areflexia Syndrome

ADIEP

Tonic Pupil
Rectum Squamous Cell Carcinoma

Squamous Cell Carcinoma Of The Rectum

Rectal Squamous Cell Carcinoma

Squamous Carcinoma Of Rectum
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04299 ELF2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus ELF2 MGD MGI:1916507
Felis catus ELF2 VGNC VGNC:61806
Macaca mulatta ELF2 VGNC VGNC:100222
Canis familiaris ELF2 VGNC VGNC:40299
Rattus norvegicus ELF2 RGD RGD:1310585
Bos taurus ELF2 VGNC VGNC:28427
Others ELF2 NCBI
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