1. Gene
  2. SLC10A4 - solute carrier family 10 member 4 Gene

SLC10A4 - solute carrier family 10 member 4 Gene

中文名称:溶质载体家族 10 成员 4

种属: Homo sapiens

同用名: P4

基因 ID: 201780 | 基因类型: protein coding

关于 SLC10A4

Cytogenetic location: 4p11 Genomic coordinates (GRCh38): 4:48,483,343-48,489,526 (from NCBI)

This gene has 2 transcripts (splice variants), 223 orthologues and 5 paralogues. Biased expression in adrenal (RPKM 2.6), brain (RPKM 1.4) and 8 other tissues.


预计会启用胆汁酸:钠同向转运体活性。预计参与胆汁酸和胆汁盐的转运以及调节神经递质加载到突触小泡中。预计在成人行为和对外源性刺激的反应的上游或内部起作用。预测位于质膜中。预计是膜的组成部分。预计在胆碱能突触中活跃;多巴胺能突触;和血清素能突触。预计是突触小泡膜的组成部分。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable bile acid:sodium symporter activity. Predicted to be involved in bile acid and bile salt transport and regulation of neurotransmitter loading into synaptic vesicle. Predicted to act upstream of or within adult behavior and response to xenobiotic stimulus. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in cholinergic synapse; dopaminergic synapse; and serotonergic synapse. Predicted to be integral component of synaptic vesicle membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC10A4 基因产物(1)

mRNA Protein Name
NM_152679.4 NP_689892.1 sodium/bile acid cotransporter 4

SLC10A4 蛋白结构


SBF: Sodium Bile acid symporter family (112 - 287)

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  • 437 a.a.
蛋白主名 其他名称

sodium/bile acid cotransporter 4

Na(+)/bile acid cotransporter 4


种属 基因名 来源 基因 ID
Bos taurus SLC10A4 VGNC VGNC:34661
Mus musculus SLC10A4 MGD MGI:3606480
Rattus norvegicus SLC10A4 RGD RGD:1309536
Felis catus SLC10A4 VGNC VGNC:65183
Macaca mulatta SLC10A4 VGNC VGNC:77553
Canis familiaris SLC10A4 VGNC VGNC:51782