Mmp2 - matrix metallopeptidase 2 Gene

中文名称：基质金属肽酶 2

种属: Rattus norvegicus

关于 Mmp2

功能概要

该基因编码的蛋白可启动纤连蛋白结合活性和肽酶活性。参与多个过程，包括细胞对雌二醇刺激的反应；循环系统发育；和生殖结构发育。位于细胞质和细胞外空间。用于研究动脉疾病（多种）；结膜炎;和短暂性脑缺血。多种疾病的生物标志物，包括急性坏死性胰腺炎；动脉疾病（多发性）；胆管疾病（多发）；脑缺血（多发）；和肝硬化（多发）。该基因的人类直系同源物与动脉疾病有关（多个）；眼病（多发）；弹性假黄瘤;和颞动脉炎。与人 MMP2（基质金属肽酶 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables fibronectin binding activity and peptidase activity. Involved in several processes, including cellular response to estradiol stimulus; circulatory system development; and reproductive structure development. Located in cytoplasm and extracellular space. Used to study artery disease (multiple); conjunctivitis; and transient cerebral ischemia. Biomarker of several diseases, including acute necrotizing pancreatitis; artery disease (multiple); bile duct disease (multiple); brain ischemia (multiple); and liver cirrhosis (multiple). Human ortholog(s) of this gene implicated in artery disease (multiple); eye disease (multiple); pseudoxanthoma elasticum; and temporal arteritis. Orthologous to human MMP2 (matrix metallopeptidase 2). [provided by Alliance of Genome Resources, Apr 2022]