2. Others MAPK/ERK Pathway Immunology/Inflammation Metabolic Enzyme/Protease PI3K/Akt/mTOR Stem Cell/Wnt Apoptosis
  3. MEK Akt E-Selectin Isotope-Labeled Compounds MMP Apoptosis ERK PI3K
  4. Trilinolein-13C54

Trilinolein-13C54 是 13C 标记的 Trilinolein (HY-128393)。Trilinolein 是一种口服有效的三酰甘油，靶向抑制 PI3K/Akt、Ras/MEK/ERK 信号通路及 MMP-2。Trilinolein 可减轻氧化应激、诱导凋亡 (apoptosis) 及抑制细胞迁移发挥作用。Trilinolein 可用于心血管疾病、脑血管疾病 (如脑缺血) 及非小细胞肺癌的研究领域。

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Trilinolein-<sup>13</sup>C<sub>54</sub>

Trilinolein-13C54 Chemical Structure

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规格 是否有货
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Other Forms of Trilinolein-13C54:

Trilinolein-13C54 相关抗体

Top Publications Citing Use of Products

查看 MEK 亚型特异性产品:

查看所有亚型
MEK1 MEK2 MEK5 MEK MAP2K4/MEK4

查看 Akt 亚型特异性产品:

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Akt Akt1 Akt2 Akt3

查看 MMP 亚型特异性产品:

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MMP-1 MMP-2 MMP-3 MMP-8 MMP-9 MMP-13 MMP-14 MMP-17 ADAM10 ADAM17 MMP-7 MMP-12 MMP-10 MMP ADAM8

查看 ERK 亚型特异性产品:

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ERK ERK1 ERK2 ERK5 ERK8

查看 PI3K 亚型特异性产品:

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PI3Kα PI3Kβ PI3Kγ PI3Kδ PI3KC2α PI3KC2β PI3KC2γ Vps34 PI3K PI3KC3 p120γ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Trilinolein-13C54 is the 13C-labeled Trilinolein (HY-128393). Trilinolein is an orally active triglyceride that inhibits the PI3K/Akt, Ras/MEK/ERK signaling pathways, and MMP-2. Trilinolein can reduce oxidative stress, induce apoptosis, and inhibit cell migration. Trilinolein can be used in the research fields of cardiovascular disease, cerebrovascular disease (such as cerebral ischemia), and non-small cell lung cancer[1][2][3][4].

产品应用

1. 该化合物可作为示踪剂。
2. 该化合物可作为 NMR、GC-MS 或 LC-MS 分析中的内标品，用于定量分析。
IC50 & Target

MMP-2

 

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物研发过程中定量分析的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而备受关注[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Trilinolein-13C54 相关抗体:
分子量

932.99

Formula

C313C54H98O6
非标记 CAS
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Trilinolein-13C54 相关分类

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  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Trilinolein-13C54MEKAktE-SelectinIsotope-Labeled CompoundsMMPApoptosisERKPI3KMitogen-activated protein kinase kinaseMAPKKMAP2KPKBProtein kinase BCD62EELAM1LECAM-2Matrix metalloproteinasesExtracellular signal regulated kinasesPhosphoinositide 3-kinaseInhibitorinhibitorinhibit

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产品名称：
Trilinolein-13C54
目录号：
HY-128393S1
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