2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. GR 55562 dihydrochloride

GR 55562 dihydrochloride 

目录号: HY-101367A 纯度: ≥99.0%
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摩尔计算器

GR 55562 (dihydrochloride) 是一种选择性的 5-HT1B 受体拮抗剂。 GR 55562 可用于神经疾病的研究。

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GR 55562 dihydrochloride Chemical Structure

GR 55562 dihydrochloride Chemical Structure

CAS No. : 159533-25-2

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规格 价格 是否有货 数量
1 mg ￥1473
In-stock
5 mg ￥3240
In-stock
10 mg ￥5184
3 - 4 周
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100 mg   询价  

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Customer Review

Other Forms of GR 55562 dihydrochloride:

GR 55562 dihydrochloride 相关抗体

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5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor 5-HT Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

GR 55562 (dihydrochloride) is a selective 5-HT1B receptor antagonist. GR 55562 can be used for the research of nerve disease[1].

体内研究
(In Vivo)

GR 55562 (0.1-10 μg/side) 进入伏隔子区域不会引起cocaine杠杆响应[1]。
GR 55562 (0.1-10 μg/side)（伏核壳或核中）的未能调节cocaine（5 mg/kg）的辨别作用[1]。
GR 55562 (1 μg/side) 显着减弱了对cocaine的辨别作用[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Wistar rats (280-300 g; n=50)[1].
Dosage: 0.1-10 μg/side
Administration: Injected intracranially; At a volume of 0.2 µl/side
Result: Did not evoke substitution for the drug with intra-accumbal shell infusion.
Did not significantly affect the discriminative stimulus effects produced by 5 mg/kg of cocaine.
GR 55562 (1 µg/side) attenuated the enhancement of cocaine discrimination evoked by a combination of intra-accumbal core CP 93129 (1 µg/side) and systemic cocaine (1.25 mg/ kg or 2.5 mg/kg).
分子量

448.39

Formula

C23H27Cl2N3O2
CAS 号
性状

固体

颜色

Off-white to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

纯度 & 产品资料
参考文献

GR 55562 dihydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GR 55562159533-25-2GR55562GR-555625-HT ReceptorSerotonin Receptor5-hydroxytryptamine Receptorserotonin (5-HT)antagonist5-HT1B receptorInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-101367A
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