2. Anti-infection
  3. RSV
  4. GS-7682

GS-7682 是一种抗病毒化合物。GS-7682 对肺病毒和小核糖核酸病毒具有抑制活性。GS-7682 可用于哮喘、慢性阻塞性肺病等呼吸道疾病的研究。

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GS-7682

GS-7682 Chemical Structure

CAS No. : 2694736-39-3

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GS-7682 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

GS-7682 is an antiviral compound. GS-7682 has inhibitory activity against pneumoviruses and picornaviruses. GS-7682 can be used in the study of respiratory diseases such as asthma and chronic obstructive pulmonary disease[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 CC50
21.1 μM
Compound: 1; GS-7682
Cytotoxicity against human A549 cells expressing hACE2 incubated for 28 hrs by Cell Titer Glo assay
Cytotoxicity against human A549 cells expressing hACE2 incubated for 28 hrs by Cell Titer Glo assay
[PMID: 39018526]
Epithelial cell CC50
8.3 μM
Compound: 1; GS-7682
Cytotoxicity against Normal human bronchial epithelial cells
Cytotoxicity against Normal human bronchial epithelial cells
[PMID: 39018526]
H1-HeLa CC50
22.2 μM
Compound: 1; GS-7682
Cytotoxicity against human H1-HeLa cells incubated for 96 hrs by Cell Titer Glo assay
Cytotoxicity against human H1-HeLa cells incubated for 96 hrs by Cell Titer Glo assay
[PMID: 39018526]
HEp-2 CC50
22.7 μM
Compound: 1; GS-7682
Cytotoxicity against human Hep-2 cells incubated for 4 to 5 days by Cell Titer Glo assay
Cytotoxicity against human Hep-2 cells incubated for 4 to 5 days by Cell Titer Glo assay
[PMID: 39018526]
LLC-MK2 CC50
> 2 μM
Compound: 1; GS-7682
Cytotoxicity against rhesus monkey LLC-MK2 cells incubated for 5 days by MTS assay
Cytotoxicity against rhesus monkey LLC-MK2 cells incubated for 5 days by MTS assay
[PMID: 39018526]
MDCK CC50
> 2 μM
Compound: 1; GS-7682
Cytotoxicity against MDCK cells by MTS assay
Cytotoxicity against MDCK cells by MTS assay
[PMID: 39018526]
MT4 CC50
3.24 μM
Compound: 1; GS-7682
Cytotoxicity against human MT4 cells incubated for 5 days by Cell Titer Glo assay
Cytotoxicity against human MT4 cells incubated for 5 days by Cell Titer Glo assay
[PMID: 39018526]
RD CC50
> 2 μM
Compound: 1; GS-7682
Cytotoxicity against human RD cells by MTS assay
Cytotoxicity against human RD cells by MTS assay
[PMID: 39018526]
分子量

672.62

Formula

C30H37N6O10P
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

GS-7682 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GS-76822694736-39-3GS7682GS 7682RSVRespiratory syncytial virusAcute respiratory viral infectionshuman metapneumovirushuman rhinovirusInhibitorinhibitorinhibit

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目录号：
HY-161877
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