1. Immunology/Inflammation Stem Cell/Wnt JAK/STAT Signaling
  2. Interleukin Related STAT
  3. GSK2618960

GSK2618960 是一种靶向 IL-7Ra/CD127 的人源单克隆抗体 (mAb)。GSK2618960 抑制 IL-7 诱导的 STAT5 磷酸化。GSK2618960 可增强 CD4 T 细胞增殖反应,并增加 PBMC 的 CD83、CD86 和 CD209 表达。GSK2618960 可用于多发性硬化症和干燥综合征的研究。推荐同型对照:Human IgG1 kappa,Isotype Control (HY-P99001)。

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GSK2618960

GSK2618960 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

GSK2618960 is a human monoclonal antibody (mAb) targeting IL-7Ra/CD127. GSK2618960 inhibits IL-7-induced STAT5 phosphorylation. GSK2618960 enhances CD4 T cell proliferation response and increases CD83, CD86, and CD209 expression in PBMCs. GSK2618960 can be used in Multiple sclerosis and Sjogren's syndrome research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001)[1].

同型

Human IgG1 kappa

推荐同型对照抗体
反应种属

Human

IC50 & Target[1]

IL7R

 

STAT5

 

基因 ID

3575  [NCBI]

Accession
应用

ELISA, FACS, Functional assay

偶联物

Unconjugated

复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
GSK2618960
目录号:
HY-P991424
需求量: