2. Immunology/Inflammation
  3. PD-1/PD-L1
  4. Human PD-L1 inhibitor V

Human PD-L1 inhibitor V 

目录号: HY-P2478 纯度: 99.04%
COA 产品使用指南

摩尔计算器

Human PD-L1 inhibitor V 是一种 human PD-1 protein 结合肽，Kd 值为 3.32 μM，可抑制人 PD-1/PD-L1 的结合。

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Custom Peptide Synthesis

Human PD-L1 inhibitor V Chemical Structure

Human PD-L1 inhibitor V Chemical Structure

CAS No. : 2815311-61-4

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3.  试用装只面向终端客户。

规格 价格 是否有货 数量
5 mg ￥1812
In-stock
10 mg ￥2900
In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Other Forms of Human PD-L1 inhibitor V:

Human PD-L1 inhibitor V 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Human PD-L1 inhibitor V, a human PD-1 protein binding peptide with a Kd value of 3.32 μM. Human PD-L1 inhibitor V inhibit the interaction of hPD-1/hPD-L1[1].

IC50 & Target

Kd: 3.32 μM (Human PD-1 protein)[1]
体外研究
(In Vitro)

Human PD-L1 inhibitor V (Ar5M_2) is a peptide designed with anchor residues Y56, R113, A121, D122 and Y123[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Human PD-L1 inhibitor V 相关抗体:
分子量

1485.71

Formula

C65H104N20O18S
CAS 号
性状

固体

颜色

White to off-white

Sequence

Leu-Asp-Tyr-Val-Asn-Arg-Arg-Lys-Met-Tyr-Gln
Sequence Shortening

LDYVNRRKMYQ
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
纯度 & 产品资料
参考文献

Human PD-L1 inhibitor V 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Human PD-L1 inhibitor V2815311-61-4PD-1/PD-L1PD-1/Programmed death-ligand 1PD-1PD-L1humanInhibitorinhibitorinhibit

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产品名称：
Human PD-L1 inhibitor V
目录号：
HY-P2478
需求量：

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