1. Others
  2. Others
  3. LP-935509

LP-935509 

目录号: HY-117626
产品使用指南

LP-935509 是一种小分子衔接蛋白-2 相关激酶1 (AAK1) 选择性和脑渗透抑制剂 (IC50=3.3 nM),一种 ATP 竞争性抑制剂,其 Ki 为 0.9 nM。 LP-935509 是 BIKE 的有效抑制剂 (IC50=14 nM) 和适度的 GAK 抑制剂 (IC50=320 nM)。 LP-935509 可逆转 SNL 手术后的疼痛。

MCE 的所有产品仅用作科学研究,我们不为任何个人用途提供产品和服务

LP-935509 Chemical Structure

LP-935509 Chemical Structure

CAS No. : 1454555-29-3

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

Size Stock
100 mg Get quote
250 mg Get quote
300 mg Get quote

* Please select Quantity before adding items.

Customer Review

Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

Description

LP-935509 is a small-molecule adapter protein-2 associated kinase 1 (AAK1) selective and brain-penetrantinhibitor (IC50=3.3 nM), a ATP-competitive inhibitor with a Ki of 0.9 nM. LP-935509 is a potent inhibitor of BIKE (IC50=14 nM) and a modest inhibitor of GAK (IC50=320 nM). LP-935509 is highly brain-penetrant and reverses fully established pain behavior following the SNL procedure[1].

IC50 & Target

IC50: 3.3 nM (AAK1); 14 nM (BIKE); 320 nM (GAK)[1]

Molecular Weight

396.44

Formula

C₂₀H₂₄N₆O₃

CAS No.

1454555-29-3

SMILES

O=C(N1CCN(C2=NC3=C(C4=CC=CN=C4OC)C=NN3C=C2)CC1)OC(C)C

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
LP-935509
目录号:
HY-117626
需求量:

LP-935509

Cat. No.: HY-117626