1. Apoptosis
  2. c-Myc
  3. m-Se3

m-Se3 是一种有效的、选择性 c-MYC 转录抑制剂,可以抑制肿瘤生长,具有抗癌活性。

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m-Se3

m-Se3 Chemical Structure

CAS No. : 2829939-44-6

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

m-Se3 is a potent and selective c-MYC transcription inhibitor that can inhibit tumor growth and has anti-cancer activity[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HCT-116 IC50
4.1 μM
Compound: m-Se3
Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
[PMID: 37036951]
HepG2 IC50
3.5 μM
Compound: m-Se3
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
[PMID: 37036951]
L02 IC50
> 100 μM
Compound: m-Se3
Cytotoxicity against human L02 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human L02 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
[PMID: 37036951]
NCM460 IC50
77.6 μM
Compound: m-Se3
Cytotoxicity against human NCM460 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human NCM460 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
[PMID: 37036951]
分子量

605.37

Formula

C29H23IN2Se

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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m-Se3
目录号:
HY-156673
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