1. Neuronal Signaling
  2. Monoamine Oxidase
  3. MAO-B-IN-15

MAO-B-IN-15 是一种选择性的 MAO-B 抑制剂 (IC50: 13.5 μM),可与 Tyr 326 残基形成 π-π 相互作用。MAO-B-IN-15 可用于帕金森病的研究。

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MAO-B-IN-15 Chemical Structure

MAO-B-IN-15 Chemical Structure

CAS No. : 2032436-79-4

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查看 Monoamine Oxidase 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MAO-B-IN-15 is a selective MAO-B inhibitor (IC50: 13.5 μM) that forms π-π interaction with Tyr 326 residue. MAO-B-IN-15 can be used in the research of Parkinson’s disease[1].

IC50 & Target[1]

hMAO-B

13.5 μM (IC50)

hMAO-A

>100 μM (IC50)

体外研究
(In Vitro)

MAO-B-IN-15 (Compound 4i, 0.01-1000 μM, 1 h) dose-dependently inhibits MAO-B activity[1].
MAO-B-IN-15 (10 μM, 24 h) has no effect on cell viability of SH-SY5Y cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

287.33

Formula

C17H18FNO2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
MAO-B-IN-15
目录号:
HY-151209
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