1. Metabolic Enzyme/Protease Apoptosis
  2. Glucosidase Dipeptidyl Peptidase Glutathione Peroxidase
  3. MPO-IN-6

MPO-IN-6 (compound ADC) 是一种亲电子试剂,具有良好的抗氧化和抗炎特性。MPO-IN-6 是一种髓过氧化物酶 (MPO) 、二肽基肽酶-4 (DPP-4) 和 α-葡萄糖苷酶 (α-GD) 抑制剂,IC50 分别为 10 μM、31.02 μM 和 46.05 μM。MPO-IN-6 是一种潜在的心血管预防剂。

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MPO-IN-6 Chemical Structure

MPO-IN-6 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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Customer Review

查看 Dipeptidyl Peptidase 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MPO-IN-6 (compound ADC) is an electrophile with good antioxidant and anti-inflammatory properties. MPO-IN-6 is a myeloperoxidase (MPO), dipeptidyl peptidase-4 (DPP-4), and α-glucosidase (α-GD) inhibitor with IC50s of 10 μM, 31.02 μM, and 46.05 μM, respectively. MPO-IN-6 is a potential cardiovascular preventive agent[1].

IC50 & Target[1]

Myeloperoxidase

10 μM (IC50)

DPP-4

31.02 μM (IC50)

α-Glucosidase

46.05 μM (IC50)

体外研究
(In Vitro)

根据 DPPH 和 ABTS•+ 清除测定结果,MPO-IN-6 (compound ADC) 相应的 IC50 值分别为 41.04 μM 和 66.13 μM[1]
在 10 mM 浓度下,MPO-IN-6 (compound ADC) 对 α-葡萄糖苷酶 (α-GD) 具有 35% 的抑制作用,随着浓度的增加,活性增加了 81%[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

328.28

Formula

C16H12N2O6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
MPO-IN-6
目录号:
HY-163332
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