1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. nAChR
  3. Mr1.1[S4Dap, C16Pen]

Mr1.1[S4Dap, C16Pen] 是一种具有高活性和选择性的 nAChR (人 α9α10 nAChR IC50 = 4.0 nM,大鼠 α9α10 nAChR IC50 = 2.7 nM) 抑制剂。Mr1.1[S4Dap, C16Pen] 可以显著缓解疼痛并且具有显著稳定性。Mr1.1[S4Dap, C16Pen] 可以用于神经性疼痛的研究。

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Custom Peptide Synthesis

Mr1.1[S4Dap, C16Pen]

Mr1.1[S4Dap, C16Pen] Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Mr1.1[S4Dap, C16Pen] is a highly active and selective nAChR (human α9α10 nAChR IC50 = 4.0 nM, rat α9α10 nAChR IC50 = 2.7 nM) inhibitor. Mr1.1[S4Dap, C16Pen] can significantly relieve pain and has significant stability. Mr1.1[S4Dap, C16Pen] can be used for the study of neuropathic pain[1].

分子量

1793.04

Formula

C71H109N25O22S4

Sequence

Gly-Cys-Cys-{Dap}-His-Pro-Ala-Cys-Ser-Val-Asn-Asn-Pro-Asp-Ile-{Pen}-NH2 (Disulfide bridge: Cys2-Cys8,Cys3-Pen)

Sequence Shortening

GCC-{Dap}-HPACSVNNPDI-{Pen}-NH2 (Disulfide bridge: Cys2-Cys8,Cys3-Pen)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Mr1.1[S4Dap, C16Pen]
目录号:
HY-P11249
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