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N-Palmitoyl dopamine  (Synonyms: PALDA)

目录号: HY-108455
产品使用指南

N-Palmitoyl dopamine (PALDA) 是一种内源性长链直链脂肪酸多巴胺,对 TRPV1 无活性。N-Palmitoyl dopamine (PALDA) 对 N-arachidonoyl-dopamine (NADA) 和 anandamide 表现出“随行”效应。

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N-Palmitoyl dopamine Chemical Structure

N-Palmitoyl dopamine Chemical Structure

CAS No. : 136181-87-8

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5 mg ¥1017
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

N-Palmitoyl dopamine (PALDA) is a endogenous, long-chain, linear fatty acid dopamide, which is inactive on TRPV1. N-Palmitoyl dopamine displays 'entourage' effects on endovanilloids N-arachidonoyl-dopamine (NADA) and anandamide[1].

体外研究
(In Vitro)

PALDA (0.1-10 μM), the EC50 of N-arachidonoyl-dopamine (NADA) is lowered from approximately 90 to approximately 30 nM. The effect on intracellular Ca2+ by another endovanilloid, N-arachidonoyl-ethanolamine (anandamide, 50 nM), is also enhanced dose-dependently by PALDA. PALDA also acted in synergy with low pH (6.0-6.7) to enhance intracellular Ca2+ via TRPV1[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

391.59

Formula

C24H41NO3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

N-Palmitoyl dopamine 相关分类

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N-Palmitoyl dopamine
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HY-108455
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