2. Peptides
  3. NF(N-Me)GA(N-Me)IL

NF(N-Me)GA(N-Me)IL  (Synonyms: Amylin (22-27) [NMeG24, NMeI26], human (IAPP))

目录号: HY-P5514
产品使用指南

摩尔计算器

NF(N-Me)GA(N-Me)IL 是一种有生物活性的肽。(该氨基酸 22 至 27 片段是人胰岛淀粉样蛋白多肽 hIAPP (NFGAIL) 的修饰，其中 G24 和 I26 处的酰胺键被 N-甲基化。在含有淀粉样蛋白核心的序列 NFGAIL 中引入两个 N-甲基残基，将这种淀粉样蛋白生成和细胞毒性序列转化为非淀粉样蛋白生成和非细胞毒性肽。该肽能够与高亲和力全长 hIAPP 结合并抑制其纤维形成。)

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Custom Peptide Synthesis

NF(N-Me)GA(N-Me)IL Chemical Structure

NF(N-Me)GA(N-Me)IL Chemical Structure

CAS No. : 409085-42-3

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NF(N-Me)GA(N-Me)IL 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

生物活性

NF(N-Me)GA(N-Me)IL is a biological active peptide. (This amino acids 22 to 27 fragment is a modification of the human islet amyloid polypeptide hIAPP (NFGAIL) with N-methylation of the amide bonds at G24 and I26. The introduction of two N-methyl rests in the amyloid-core-containing sequence NFGAIL converts this amyloidogenic and cytotoxic sequence into non-amyloidogenic and non-cytotoxic peptide. The peptide is able to bind with high-affinity full-length hIAPP and to inhibit its fibrillogenesis.)

分子量

661.79

Formula

C32H51N7O8
CAS 号
Sequence

Asn-Phe-{Sar}-Ala-{Ile(N-Me)}-Leu
Sequence Shortening

NF-{Sar}-A-{Ile(N-Me)}-L
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NF(N-Me)GA(N-Me)IL409085-42-3Amylin (22-27) [NMeG24, NMeI26], human (IAPP)OthersInhibitorinhibitorinhibit

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