1. Anti-infection
  2. Parasite
  3. Niclofolan

Niclofolan  (Synonyms: BAY 9015; Menichlopholan; Menichlofolan; Bilevon)

目录号: HY-113715 纯度: 99.55%
COA 产品使用指南

Niclofolan (BAY 9015) 是一种具有口服活性的驱虫剂。Niclofolan 可用于寄生虫感染相关的研究。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Niclofolan Chemical Structure

Niclofolan Chemical Structure

CAS No. : 10331-57-4

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Free Sample (0.1 - 0.2 mg)   Apply now  
10 mM * 1 mL in DMSO ¥1100
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5 mg ¥1000
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10 mg ¥1600
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25 mg ¥3200
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50 mg ¥5100
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100 mg ¥8100
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Niclofolan (BAY 9015) is an orally active anthelmintic agent. Niclofolan can be used in the research of parasite infection[1][2][3].

体外研究
(In Vitro)

Niclofolan (0.12 mg/mL, 60 min) is effective against Gyrodactylus sp. under in vitro conditions[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[3]

Cell Line: Gyrodactylus sp. (parasite)
Concentration: 0.12 mg/mL
Incubation Time: 60 min
Result: Reduced the number of live Gyrodactylus sp. By 100%.
体内研究
(In Vivo)

Niclofolan (2 mg/kg, intramuscular injection) is effective against fasciola hepatica infected sheep[2].
Niclofolan (1 or 2 mg/kg, oral gavage ) shows therapeutic effects against P.iloktsuenesis infected rats[4].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: fasciola hepatica infected sheep[2]
Dosage: 2 mg/kg
Administration: Intramuscular injection
Result: Showed effectiveness against the infection and produced no untoward effects except for transient signs of pain at the site of injection.
Animal Model: Rats infected with P.iloktsuenesis[4]
Dosage: 1 mg/kg, daily for 3 days; 2 mg/kg every other day for 2 times.
Administration: Oral gavage
Result: Reduced the worms in rats.
分子量

345.09

Formula

C12H6Cl2N2O6

CAS 号
性状

固体

颜色

Light yellow to yellow

中文名称

硝氯酚;羊肝酯

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据
In Vitro: 

DMSO 中的溶解度 : 100 mg/mL (289.78 mM; 超声助溶 (<60°C); 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.8978 mL 14.4890 mL 28.9779 mL
5 mM 0.5796 mL 2.8978 mL 5.7956 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

Niclofolan 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8978 mL 14.4890 mL 28.9779 mL 72.4449 mL
5 mM 0.5796 mL 2.8978 mL 5.7956 mL 14.4890 mL
10 mM 0.2898 mL 1.4489 mL 2.8978 mL 7.2445 mL
15 mM 0.1932 mL 0.9659 mL 1.9319 mL 4.8297 mL
20 mM 0.1449 mL 0.7244 mL 1.4489 mL 3.6222 mL
25 mM 0.1159 mL 0.5796 mL 1.1591 mL 2.8978 mL
30 mM 0.0966 mL 0.4830 mL 0.9659 mL 2.4148 mL
40 mM 0.0724 mL 0.3622 mL 0.7244 mL 1.8111 mL
50 mM 0.0580 mL 0.2898 mL 0.5796 mL 1.4489 mL
60 mM 0.0483 mL 0.2415 mL 0.4830 mL 1.2074 mL
80 mM 0.0362 mL 0.1811 mL 0.3622 mL 0.9056 mL
100 mM 0.0290 mL 0.1449 mL 0.2898 mL 0.7244 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Niclofolan
目录号:
HY-113715
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