1. Cell Cycle/DNA Damage Epigenetics
  2. Sirtuin
  3. Ophiopogonin D'

Ophiopogonin D'  (Synonyms: 麦冬皂苷 D')

目录号: HY-N3504 纯度: 99.85%
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Ophiopogonin D' 是从麦冬 (Ophiopogon japonicus) 的块茎中分离的,是一种罕见的天然存在的 C29 甾体糖苷。Ophiopogonin D' 针对两种人肿瘤细胞系 MG-63 和 SNU387 的有细胞毒活性,IC50 分别为 3.09 μM 和 3.63 μM。Ophiopogonin D' 以剂量依赖方式激活 SIRT1

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Ophiopogonin D' Chemical Structure

Ophiopogonin D' Chemical Structure

CAS No. : 65604-80-0

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  • 生物活性

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生物活性

Ophiopogonin D', isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C29 steroidal glycoside. Ophiopogonin D' shows cytotoxic activity against two human tumor cell lines MG-63 and SNU387 with IC50s of 3.09 μM and 3.63 μM, respectively[1]. Ophiopogonin D' activates SIRT1 in a dose-dependent manner[2].

IC50 & Target

SIRT1

 

分子量

855.02

Formula

C44H70O16

CAS 号
性状

固体

颜色

White to off-white

中文名称

麦冬皂苷 D'

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料
参考文献

Ophiopogonin D' 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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