1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugate
  3. Pomalidomide-C7-COOH

Pomalidomide-C7-COOH 

目录号: HY-133799
产品使用指南

Pomalidomide-C7-COOH 是一种合成的 E3 连接酶配体-linker 偶联物,是 PROTAC BCL-XL 降解剂合成的中间体。

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Pomalidomide-C7-COOH Chemical Structure

Pomalidomide-C7-COOH Chemical Structure

CAS No. : 2225940-51-0

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Description

Pomalidomide-C7-COOH is a synthesized E3 ligase cereblon ligand-linker conjugate. Pomalidomide-C7-COOH is an intermediate for the synthesis of PROTAC BCL-XL degraders[1].

IC50 & Target

Cereblon[1]

Molecular Weight

415.44

Formula

C₂₁H₂₅N₃O₆

CAS No.

2225940-51-0

SMILES

O=C(O)CCCCCCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Pomalidomide-C7-COOHE3 Ligase Ligand-Linker ConjugateE3ligasecereblonligandlinkerconjugatePROTACBCL-XLInhibitorinhibitorinhibit

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产品名称:
Pomalidomide-C7-COOH
目录号:
HY-133799
需求量: