1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. Propargyl-PEG1-SS-alcohol

Propargyl-PEG1-SS-alcohol 是一种可降解 (cleavable) 的含 1 个单元 PEG 的 ADC linker,可用于合成抗体偶联活性分子 (ADC)。Propargyl-PEG1-SS-alcohol 是一种点击化学试剂。它含有 Alkyne 基团,可以和含有 Azide 基团的分子发生铜催化的叠氮-炔环加成反应 (CuAAc)。

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Propargyl-PEG1-SS-alcohol Chemical Structure

Propargyl-PEG1-SS-alcohol Chemical Structure

CAS No. : 1391914-41-2

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Propargyl-PEG1-SS-alcohol is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG1-SS-alcohol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC50 & Target

Disulfide Cleavable Linker

 

Cleavable Linker

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

192.30

Formula

C7H12O2S2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Propargyl-PEG1-SS-alcohol 相关分类

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Propargyl-PEG1-SS-alcohol
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