2. Apoptosis Metabolic Enzyme/Protease Immunology/Inflammation NF-κB
  3. Apoptosis Reactive Oxygen Species (ROS)
  4. R24

R24 是一种类黄酮衍生物。R24 具有强大的抗血管生成和抗增殖作用。R24 诱导了细胞凋亡 (apoptosis) 并促进 ROS 的产生。R24 可用于研究如肺癌和结直肠癌等癌症。

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R24

R24 Chemical Structure

CAS No. : 151417-66-2

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R24 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

R24 is a type of flavonoid derivative. R24 exhibits strong anti-angiogenic and anti-proliferative effects. R24 induces cell apoptosis and promotes the production of reactive oxygen species (ROS). R24 can be used for the study of cancers such as lung cancer and colorectal cancer[1].
体外研究
(In Vitro)

R24 对 A549、AsPC-1、HCT-116 和 PC-3 细胞系的 IC50 值分别为 3.44、3.59、1.22 和 11.83 μM[1]。
R24 (2.5 μM，48 小时) 可诱导 A549 细胞凋亡，并增加细胞在亚 G1 期的积累[1]。
R24 (2.5-10 μM，30 分钟) 可剂量依赖性地促进 A549 细胞内活性氧 (ROS) 的产生[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

R24 相关抗体:

Apoptosis Analysis[1]

Cell Line: A549 cells
Concentration: 2.5 μM
Incubation Time: 48 h
Result: Increased early and late apoptosis rate.

Cell Cycle Analysis[1]

Cell Line: A549 cells
Concentration: 2.5 μM
Incubation Time: 48 h
Result: Increased cell accumulation in the sub-G1 phase.
体内研究
(In Vivo)

R24 (60 μg/枚蛋，48 小时) 可破坏鸡胚的血管生成[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

340.33

Formula

C19H16O6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

R24 相关分类

  • 摩尔计算器

  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

R24151417-66-2R 24R-24ApoptosisReactive Oxygen Species (ROS)FlavonoidAngiogenesisReactive oxygen species,Tumor vasculatureInhibitorinhibitorinhibit

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