2. Neuronal Signaling GPCR/G Protein Metabolic Enzyme/Protease
  3. Cannabinoid Receptor Cytochrome P450
  4. (±)5(6)-EET Ethanolamide

(±)5(6)-EET Ethanolamide 是 Anandamide (HY-10863) 经细胞色素 P450 酶氧化生成的代谢产物，也是一种选择性大麻素受体 2 (CB2) 激动剂。(±)5(6)-EET Ethanolamide 对人 CB1 和 CB2 的 Ki 值分别为 11.4 μM 和 8.9 nM。(±)5(6)-EET Ethanolamide 可用于免疫调节和神经炎症方面的研究。

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(±)5(6)-EET Ethanolamide

(±)5(6)-EET Ethanolamide Chemical Structure

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(±)5(6)-EET Ethanolamide 相关抗体

Top Publications Citing Use of Products

查看 Cannabinoid Receptor 亚型特异性产品:

查看所有亚型
CB1 CB2

查看 Cytochrome P450 亚型特异性产品:

查看所有亚型
CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP1A2 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(±)5(6)-EET Ethanolamide is a metabolite of Anandamide (HY-10863) generated via oxidation by cytochrome P450 enzymes. (±)5(6)-EET Ethanolamide is also a selective cannabinoid receptor 2 (CB2) agonist. (±)5(6)-EET Ethanolamide has Ki values of 11.4 μM and 8.9 nM for human CB1 and CB2, respectively . (±)5(6)-EET Ethanolamide can be used in research on immunomodulation and neuroinflammation[1].

IC50 & Target[1]

hCB1-R

11.4 μM (Ki)

hCB2-R

8.9 nM (Ki)

分子量

363.53

Formula

C22H37NO3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(±)5(6)-EET Ethanolamide 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(±)5(6)-EET EthanolamideCannabinoid ReceptorCytochrome P450CYPsAnandamidecannabinoid receptor 2immunomodulationneuroinflammationInhibitorinhibitorinhibit

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