1. Epigenetics TGF-beta/Smad
  2. PKC
  3. Ro 31-8220 mesylate (Standard)

Ro 31-8220 mesylate (Standard) 

目录号: HY-13866R 纯度: ≥98%
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Ro 31-8220 (mesylate) (Standard) 是 Ro 31-8220 (mesylate) 的分析标准品。本产品用于研究及分析应用。Ro 31-8220 mesylate 是一种有效的 PKC 抑制剂,抑制 PKCα,PKCβI,PKCβII,PKCγ,PKCε 和大鼠大脑 PKCIC50 值为 5,24,14,27,24 和 23 nM,也可抑制 MAPKAP-K1b,MSK1,S6K1 和 GSK3β,IC5

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Ro 31-8220 mesylate (Standard) Chemical Structure

Ro 31-8220 mesylate (Standard) Chemical Structure

CAS No. : 138489-18-6

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生物活性

Ro 31-8220 (mesylate) (Standard) is the analytical standard of Ro 31-8220 (mesylate). This product is intended for research and analytical applications. Ro 31-8220 mesylate is a potent PKC inhibitor, with IC50s of 5, 24, 14, 27, 24 and 23 nM for PKCα, PKCβI, PKCβII, PKCγ, PKCε and rat brain PKC, respectively. Ro 31-8220 also significantly inhibits MAPKAP-K1b, MSK1, S6K1 and GSK3β (IC50s, 3, 8, 15, and 38 nM, respectively), with no effect on MKK3, MKK4, MKK6 and MKK7.

分子量

553.65

Formula

C26H27N5O5S2

CAS 号
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Ro 31-8220 mesylate (Standard)
目录号:
HY-13866R
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