1. Screening Libraries
  2. Neurotransmitter Receptor Compound Library

神经递质受体化合物库 - Neurotransmitter Receptor Compound Library

Cat. No.: HY-L062
Library Contents: XLSX PDF SDF

神经递质受体(neurotransmitter receptors,NT receptors)是一类广泛存在的膜蛋白,可以与神经递质结合,进行神经信号传导。主要有两大类神经递质受体:促离子型受体和促代谢型受体。促离子型受体是一种配体门控离子通道,受体蛋白包括一个神经递质结合位点和一个离子通道。神经递质(配体)与结合位点的结合引起受体结构的构象变化,从而使离子通道打开。促代谢型受体是一类G蛋白偶联受体(GPCR),神经递质与受体结合后可以促发第二信使介导的细胞效应。

神经递质受体是很多神经系统疾病的重要靶点。许多神经活性药物通过改变神经递质受体发挥作用。更好地理解神经递质受体在疾病中的作用机制可以加快疾病的治疗。

MCE 提供 1069 种神经递质受体相关的化合物,可以用于神经系统疾病药物的筛选。

我们将在明确您的产品用途后,向符合资质的客户通过定制合成服务的方式提供 MCE 神经递质受体化合物库,我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中,1054 个产品以 10 mM 浓度提供,15 个产品以 2 mM 浓度提供。

溶液包装中,我们对于溶液状态稳定且溶解度不低于 10 mM 的产品,提供 10 mM 溶液;对于溶液状态稳定且溶解度介于 2~10 mM 的产品,我们提供 2 mM 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
Size (Pre-dissolved Solution or Solid) Price Stock
30 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

Get quote In-stock
50 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

Get quote In-stock
100 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

Get quote In-stock
2 × 100 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

Get quote In-stock

Please contact us at

sales@MedChemExpress.cn

Top Publications Citing Use of Products
  • Description

  • Product Details

  • Documentation

Description
& Advantages

•   A unique collection of 1069 small molecule modulators used for neurological diseases research.

•   The library contains compounds targeting neurotransmitter receptors including mAChR, nAChR, Adrenergic Receptor, Dopamine Receptor, etc.

•   A useful tool for neurological diseases drug discovery.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some inhibitors have been approved by FDA.

•   Structurally diverse, medicinally active, and cell permeable.

•   Rich documentation with structure, IC50, and summary.

•   NMR and HPLC validated to ensure high purity.

•   All compounds are in stock and continuously updated.

Product Details
Formulation:
A collection of 1069 neurotransmitter receptor compounds supplied as pre-dissolved Solutions or Solid
Solution: 1054 compounds supplied in 10 mM solution, 15 compounds supplied in 2 mM solution.
Container:
96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
-80°C
Shipping:
Blue ice
Documentation

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

* Container:

       留言给我们:

    Bulk Inquiry

    Inquiry Information

    产品名称:
    Neurotransmitter Receptor Compound Library
    目录号:
    HY-L062
    需求量:

    Request SDF File

    Please enter your email address. We will send your requested SDF file to you as soon as possible.

    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack
    • 96-well Storage Tubes with Rack