1. Antibody-drug Conjugate/ADC Related
  2. Drug-Linker Conjugates for ADC
  3. Sulfo-PDBA-DM4

Sulfo-PDBA-DM4 

目录号: HY-128954
产品使用指南

Sulfo-PDBA-DM4 是 drug-linker conjugate,由连接桥 Sulfo-PDBA 和 毒性分子 DM4 连接而成的,可用来制备抗体偶联药物。Sulfo-PDBA 是一种谷氨酸可裂解的 linker。

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Sulfo-PDBA-DM4 Chemical Structure

Sulfo-PDBA-DM4 Chemical Structure

CAS No. : 1461704-01-7

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Description

Sulfo-PDBA-DM4 is a drug-linker conjugate composed of a potent a tubulin inhibitor DM4 and a linker Sulfo-PDBA to make antibody drug conjugate (ADC). Sulfo-PDBA is a gluthatione cleavable linker.

IC50 & Target

Maytansinoids

 

Molecular Weight

978.58

Formula

C₄₂H₆₀ClN₃O₁₅S₃

CAS No.

1461704-01-7

SMILES

C[C@]12[C@H]([C@@H]([C@](O3)([H])C[C@]([C@](/C=C/C=C(C)/CC4=CC(N(C)C(C[C@]2([H])OC([C@H](C)N(C)C(CCC(C)(C)SSCCC(C(O)=O)S(=O)(O)=O)=O)=O)=O)=C(C(OC)=C4)Cl)([H])OC)(NC3=O)O)C)O1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Sulfo-PDBA-DM4Drug-Linker Conjugates for ADCInhibitorinhibitorinhibit

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产品名称:
Sulfo-PDBA-DM4
目录号:
HY-128954
需求量: