2. Others Neuronal Signaling Membrane Transporter/Ion Channel
  3. nAChR Isotope-Labeled Compounds
  4. Sulfoxaflor-d3

Sulfoxaflor-d3  (Synonyms: 氟啶虫胺腈-d3； 啶虫胺腈-d3； 砜虫啶-d3)

目录号: HY-118504S
产品使用指南 技术支持

Sulfoxaflor-d3 是 Sulfoxaflor (HY-118504) 的氘代物。Sulfoxaflor 是一种口服有效的、昆虫烟碱型乙酰胆碱受体 (nAChR) 的完全激动剂，靶向 α-银环蛇毒素不敏感的 nAChR1 和 nAChR2 亚型。Sulfoxaflor 对 nACh 的结合，不受 d-Tubocurarine (HY-125901) 抑制，但可被 Mecamylamine (HY-B1395A) 部分抑制。Sulfoxaflor 通过激活 nAChR 引发内向电流，导致昆虫神经毒性。Sulfoxaflor 可用于农业害虫防治及农药毒理学、昆虫神经受体药理学等领域的研究。

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Sulfoxaflor-d<sub>3</sub>

Sulfoxaflor-d3 Chemical Structure

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Sulfoxaflor-d3 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Sulfoxaflor-d3 is the deuterium labeled Sulfoxaflor (HY-118504). Sulfoxaflor is an orally active full agonist of insect nicotinic acetylcholine receptors (nAChRs), targeting the α-bungarotoxin-insensitive nAChR1 and nAChR2 subtypes. Sulfoxaflor binding to nACh is not inhibited by d-Tubocurarine (HY-125901), but is partially inhibited by Mecamylamine (HY-B1395A). Sulfoxaflor induces inward currents by activating nAChRs, leading to insect neurotoxicity. Sulfoxaflor can be used in the research of agricultural pest control, pesticide toxicology, insect neural receptor pharmacology, etc[1][2].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Sulfoxaflor-d3 相关抗体:
分子量

280.28

Formula

C10H7D3F3N3OS
非标记 CAS
中文名称

氟啶虫胺腈-d3； 啶虫胺腈-d3； 砜虫啶-d3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Sulfoxaflor-d3 相关分类

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  • 稀释计算器

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Keywords:

Sulfoxaflor-d3氟啶虫胺腈-d3 啶虫胺腈-d3 砜虫啶-d3nAChRIsotope-Labeled CompoundsNicotinic acetylcholine receptorsInhibitorinhibitorinhibit

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