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  4. Tadocizumab

Tadocizumab  (Synonyms: C4G1; YM-337)

目录号: HY-P99560

摩尔计算器

Tadocizumab (C4G1; YM-337) 是一种靶向整合素 αIIbβ3 的人源化单克隆抗体。Tadocizumab 具有抗血小板和抗血栓作用，可用于心血管疾病研究。

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Tadocizumab Chemical Structure

Tadocizumab Chemical Structure

CAS No. : 339086-80-5

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Tadocizumab 相关抗体

Top Publications Citing Use of Products

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αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α9β1 αIIbβ3 α4β7 αLβ2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tadocizumab (C4G1; YM-337) is a humanized monoclonal antibody tageting integrin αIIbβ3. Tadocizumab has antiplatelet and antithrombotic effects, and can be used for cardiovascular disease research[1][2].

IC50 & Target[1]

GPIIb/IIIa

 

体外研究
(In Vitro)

Tadocizumab (YM-337) 显着抑制体外 ADP 诱导的血小板聚集，并完全抑制花生四烯酸诱导的血小板聚集[1]。
Tadocizumab (YM-337) 抑制人血小板粘附到 von Willebrand 因子、纤维蛋白原、纤连蛋白和内皮下基质[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Tadocizumab 相关抗体:
体内研究
(In Vivo)
CAS 号
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Tadocizumab 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tadocizumab339086-80-5C4G1 YM-337YM337YM 337YM-337Integrincardiovascular systemintegrin αIIbβ3antiplatelet and antithrombotic effectsplatelet aggregationInhibitorinhibitorinhibit

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