1. PROTAC Autophagy Apoptosis
  2. E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis
  3. Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride

Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride 

目录号: HY-112617B
产品使用指南

Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride (Cereblon Ligand-Linker Conjugates 10 TFA) 结合了 E3 连接酶配体和 linker,可作为免疫调节剂研究癌症。

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Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride Chemical Structure

Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride Chemical Structure

CAS No. : 2376990-30-4

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规格 价格 是否有货 数量
25 mg ¥1200
In-stock
50 mg ¥1860
In-stock
100 mg ¥2890
In-stock
500 mg ¥8670
In-stock
1 g   询价  
5 g   询价  

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Customer Review

查看 E3 Ligase Ligand-Linker Conjugates 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride incorporates an E3 ligase ligand and a linker, can be an immunomodulater for the treatment of cancer[1].

IC50 & Target

Cereblon

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

498.91

Formula

C21H27ClN4O8

CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride
目录号:
HY-112617B
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