1. Cell Cycle/DNA Damage Cytoskeleton
  2. Microtubule/Tubulin
  3. THK-5105

THK-5105 是一种芳基喹啉衍生物,对 tau 原纤维具有高结合亲和力。THK-5105 对 tau 蛋白聚集体和富含 tau 的阿尔茨海默病 (AD) 脑匀浆具有高结合亲和力。18F-THK-5105 有有潜力作为 tau 成像 PET 探针。

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THK-5105 Chemical Structure

THK-5105 Chemical Structure

CAS No. : 1374107-46-6

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  • 生物活性

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  • 参考文献

生物活性

THK-5105, an arylquinoline derivative, displays high binding affinity to tau fibrils. THK-5105 has high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD)  brain homogenates. 18F-THK-5105 has the potential to act as a tau imaging PET probe[1].

分子量

340.39

Formula

C20H21FN2O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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产品名称:
THK-5105
目录号:
HY-101181
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