2. Cell Cycle/DNA Damage
  3. Topoisomerase
  4. Topoisomerase II inhibitor 5

Topoisomerase II inhibitor 5 (Compound E24) 是一种具有抗癌活性的 DNA topoisomerase II 抑制剂。

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Topoisomerase II inhibitor 5 Chemical Structure

Topoisomerase II inhibitor 5 Chemical Structure

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Topoisomerase II inhibitor 5 相关抗体

Top Publications Citing Use of Products

查看 Topoisomerase 亚型特异性产品:

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Topoisomerase Topo I Topo II

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Topoisomerase II inhibitor 5 (Compound E24) is a DNA topoisomerase II inhibitor with anticancer activities[1].

IC50 & Target

Topoisomerase II

 

体外研究
(In Vitro)

Topoisomerase II inhibitor 5 (Compound E24) (0-20 μM, 72 h) shows antiproliferative activities against cancer cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Topoisomerase II inhibitor 5 相关抗体:

Cell Proliferation Assay[1]

Cell Line: SW480, HCT116 and HeLa
Concentration: 0-20 μM
Incubation Time: 72 h
Result: Showed antiproliferative activities with IC50 values of 1.2 ± 0.3, 0.7 ± 0.05 and 1.2 ± 0.04 μM against SW480, HCT116 and HeLa cells, respectively.
分子量

473.52

Formula

C26H27N5O4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Topoisomerase II inhibitor 5 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Topoisomerase II inhibitor 5Topoisomerase II inhibitor5Topoisomerase II inhibitor-5TopoisomeraseanticancerSW480HCT116HeLaInhibitorinhibitorinhibit

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产品名称：
Topoisomerase II inhibitor 5
目录号：
HY-143281
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