1. Immunology/Inflammation
  2. MHC
  3. TpD

TpD 是一种嵌合型的辅助 T 细胞表位 (T-helper epitope)。TpD 具有一个特殊的位点,可以被胱天蛋白酶切割。使用 TpD 进行免疫接种能够产生强烈的抗体反应。TpD 促进动物和人类的长期 CD4 免疫反应。TpD 能很好地结合多种人类 MHC II 类型,主要是 HLA-DRB1。它还结合其他一些 HLA 等位基因,如 DRB3、DRB4、DRB5、DP 和 DQ。TpD 可用于增强肽疫苗的免疫反应。

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TpD

TpD Chemical Structure

CAS No. : 1273551-45-3

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生物活性

TpD is a chimeric T-helper epitope. TpD has a special site that cathepsin can cut. Immunization with TpD produces a strong antibody response. TpD promotes long-term CD4 immune responses in animals and humans. TpD binds well to many human MHC class II types, mainly HLA-DRB1. It also binds some other HLA alleles like DRB3, DRB4, DRB5, DP, and DQ. TpD can be used to improve the immune response of peptide vaccines[1].

分子量

3464.21

Formula

C158H264N38O42S3

CAS 号
Sequence

Ile-Leu-Met-Gln-Tyr-Ile-Lys-Ala-Asn-Ser-Lys-Phe-Ile-Gly-Ile-Pro-Met-Gly-Leu-Pro-Gln-Ser-Ile-Ala-Leu-Ser-Ser-Leu-Met-Val-Ala-Gln

Sequence Shortening

ILMQYIKANSKFIGIPMGLPQSIALSSLMVAQ

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
TpD
目录号:
HY-P11090
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