1. Immunology/Inflammation NF-κB Stem Cell/Wnt TGF-beta/Smad Metabolic Enzyme/Protease
  2. NOD-like Receptor (NLR) Reactive Oxygen Species TGF-beta/Smad Endogenous Metabolite
  3. Trimethylamine-N-oxide-13C3

Trimethylamine-N-oxide-13C3  (Synonyms: 三甲胺N-氧化物 13C3)

目录号: HY-116084S1
产品使用指南

Trimethylamine-N-oxide-13C3 是一种 13C 标记的 Trimethylamine N-oxide。Trimethylamine N-oxide 是一种膳食胆碱和其他含三甲胺营养素的肠道微生物依赖性代谢产物。Trimethylamine N-oxide 通过激活 ROS/NLRP3 炎性体诱导炎症。Trimethylamine N-oxide 还通过激活 TGF-β/smad2 信号通路来加速成纤维细胞的分化并诱导心脏纤维化。

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Trimethylamine-N-oxide-<sup>13</sup>C<sub>3</sub> Chemical Structure

Trimethylamine-N-oxide-13C3 Chemical Structure

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规格 是否有货
1 mg
询价
5 mg
询价

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Other Forms of Trimethylamine-N-oxide-13C3:

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Trimethylamine-N-oxide-13C3 is the 13C-labeled Trimethylamine N-oxide. Trimethylamine N-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide induces inflammation by activating the ROS/NLRP3 inflammasome. Trimethylamine N-oxide also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway[1][2][3].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

78.09

Formula

13C3H9NO

中文名称

三甲胺N-氧化物 13C3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Trimethylamine-N-oxide-13C3
目录号:
HY-116084S1
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