2. Antibody-drug Conjugate/ADC Related PROTAC
  3. ADC Linker PROTAC Linkers
  4. Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine

Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine 

目录号: HY-21577
COA 产品使用指南

摩尔计算器

Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine 是一种可降解 (cleavable) 的 PEG 的 ADC linker，可用于合成抗体偶联活性分子 (ADC)。Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine 也是一种 PROTAC linker，属于 PEG 和 Alkyl/ether 类，可用于合成 PROTAC 分子。

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Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine Chemical Structure

Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine Chemical Structure

CAS No. : 175724-30-8

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规格 价格 是否有货 数量
250 mg ￥100
In-stock
1 g ￥251
In-stock
5 g ￥972
In-stock
10 g ￥1650
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50 g   询价  

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Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine 相关抗体

Top Publications Citing Use of Products

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PEG Linkers Alkyl-Chain Linkers Alkyl/ether Linkers

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane is also a PEG/Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

Cleavable Linker

 

Alkyl/ether

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine 相关抗体:
分子量

505.64

Formula

C25H47NO9
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料

纯度: ≥98.0%

COA (191 KB)

产品使用指南 (1538 KB)
参考文献

Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine175724-30-8ADC LinkerPROTAC LinkersAntibody-drug conjugates linkerPEGADClinkerPROTACcleavableInhibitorinhibitorinhibit

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Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine
目录号：
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