1. Metabolic Enzyme/Protease
  2. ROR
  3. XY101

XY101 

目录号: HY-128604
产品使用指南

XY101 是一种有效选择性的、代谢稳定的口服 RORγ 反向激动剂,IC50 为 30 nM,Kd 为 380 nM。

MCE 的所有产品仅用作科学研究,我们不为任何个人用途提供产品和服务

XY101 Chemical Structure

XY101 Chemical Structure

CAS No. : 2349368-16-5

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

Size Stock
100 mg Get quote
250 mg Get quote
500 mg Get quote

* Please select Quantity before adding items.

Customer Review

Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

Description

XY101 is a potent, selective, metabolically stable and orally available RORγ inverse agonist with an IC50 of 30 nM and a Kd of 380 nM[1].

IC50 & Target

IC50: 30 nM (RORγ)[1]
Kd: 380 nM (RORγ)[1]

In Vitro

XY101 potently inhibits cell growth, colony formation, and the expression of androgen receptor (AR), AR-V7 and prostate-specific antigen (PSA)[1].

In Vivo

XY101 exhibits significant antitumor activities during the treatment period with tumor growth inhibition and is well tolerated without obvious body weight loss[1].

Molecular Weight

563.48

Formula

C₂₅H₂₀F₇NO₄S

CAS No.

2349368-16-5

SMILES

O=S(C1=CC=C(CC(NC2=CC=C(C3=C(F)C=C(C(O)(C(F)(F)F)C(F)(F)F)C=C3)C=C2)=O)C=C1)(CC)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
XY101
目录号:
HY-128604
需求量:

XY101

Cat. No.: HY-128604